Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | AHCY | P23526 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065501 | 0.83 | EGFR (0.46) | EGFRADORA2AENPP1NT5EPI4KA | |
| SCHEMBL4089586 | 0.83 | EGFR (0.46) | EGFRADORA2AENPP1NT5EPI4KA | |
| SCHEMBL13723744 | 0.79 | ENPP1 (0.57) | EGFRADORA2AENPP1NT5EPI4KA | |
| SCHEMBL13724155 | 0.78 | MEN1 (0.65) | EGFRADORA2AENPP1NT5EPI4KA | |
| Hydrochloric Acid SCHEMBL4095590 | 0.76 | MAPK1 (0.64) | EGFRADORA2AENPP1NT5EPI4KA | |
| SCHEMBL4094131 | 0.76 | EGFR (0.64) | EGFRADORA2AENPP1NT5EPI4KA | |
| SCHEMBL13749328 | 0.75 | ENPP1 (0.53) | EGFRADORA2AENPP1NT5EPI4KA | |
| SCHEMBL4094997 | 0.74 | ADORA2A (0.61) | EGFRADORA2AENPP1NT5EPI4KA | |
| SCHEMBL9426463 | 0.74 | ENPP1 (0.61) | EGFRADORA2AENPP1NT5EPI4KA | |
| SCHEMBL5134015 | 0.73 | HPGD (0.45) | MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001488-A2 | PREVENTION AND TREATMENT OF CANCER AND OTHER DISEASES | Alt Solutions, Inc. (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007106561-A2 | PREVENTION AND TREATMENT OF CANCER AND OTHER DISEASES | ALT SOLUTIONS, INC. (US) | 2007-09-20 | — | — | WO | disclosed |