Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CHKA | P35790 | 7/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117970 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4ESMN1; SMN2CHKABCHE | |
| SCHEMBL27862519 | 0.90 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2CHKAMAPT | |
| SCHEMBL28210915 | 0.84 | CNR2 (0.49) | ALDH1A1KDM4ESMN1; SMN2CHKAMAPT | |
| SCHEMBL6065386 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4ESMN1; SMN2CHKABCHE | |
| SCHEMBL6675490 | 0.81 | ADRB1 (0.53) | ALDH1A1KDM4EUSP2HSD17B10LMNA | |
| SCHEMBL6675497 | 0.81 | ADRB1 (0.53) | ALDH1A1KDM4EUSP2HSD17B10LMNA | |
| SCHEMBL27862322 | 0.80 | PRMT6 (0.58) | ALDH1A1KDM4ECHKABCHEACHE | |
| SCHEMBL15551035 | 0.79 | TRIM24 (0.61) | ALDH1A1KDM4ESMN1; SMN2CHKABCHE | |
| SCHEMBL9915870 | 0.79 | CHKA (0.65) | ALDH1A1KDM4ESMN1; SMN2CHKABCHE | |
| SCHEMBL11859247 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2CHKABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080146574-A1 | Heterocycle Substituted Carboxylic Acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC | 2008-06-19 | — | — | US | claimed |
| EP-1628970-A2 | HETEROCYCLE SUBSTITUTED CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B | The Institutes of Pharmaceutical Discovery, LLC (US) | 2006-03-01 | — | — | EP | claimed |
| US-20050004114-A1 | Heterocycle substituted carboxylic acids | INSTITUTE FOR DIABETES DISCOVERY, L.L.C. | 2005-01-06 | — | — | US | claimed |
| WO-2004099192-A2 | HETEROCYCLE SUBSTITUTED CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B | THE INSTITUTES OF PHARMACEUTICAL DISCOVERY, LLC (US) | 2004-11-18 | — | — | WO | claimed |
| US-5574037-A | MODULATED BY SINO-ATRIAL NODE, ANTIISCHEMIC AGENT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1996-11-12 | — | — | US | claimed |
| CN-102382257-B | Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer | SUMITOMO CHEMICAL CO | 2015-02-11 | — | — | CN | disclosed |
| CN-104334629-A | Tread rubber composition and pneumatic tire | SUMITOMO RUBBER IND | 2015-02-04 | — | — | CN | disclosed |
| CN-104098744-A | Conjugated diene based polymer, and polymer composition containing the polymer | SUMITOMO CHEMICAL CO | 2014-10-15 | — | — | CN | disclosed |
| CN-104045768-A | CONJUGATED DIENE BASED POLYMER, AND POLYMER COMPOSITION CONTAINING THE POLYMER | SUMITOMO CHEMICAL CO | 2014-09-17 | — | — | CN | disclosed |
| CN-104045769-A | CONJUGATED DIENE BASED POLYMER, AND POLYMER COMPOSITION CONTAINING THE POLYMER | SUMITOMO CHEMICAL CO | 2014-09-17 | — | — | CN | disclosed |
| CN-102432759-A | Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer | SUMITOMO CHEMICAL CO | 2012-05-02 | — | — | CN | disclosed |
| CN-102382258-A | Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer | SUMITOMO CHEMICAL CO | 2012-03-21 | — | — | CN | disclosed |
| CN-102382257-A | Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer | SUMITOMO CHEMICAL CO | 2012-03-21 | — | — | CN | disclosed |
| US-20080146574-A1 | Heterocycle Substituted Carboxylic Acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC | 2008-06-19 | — | — | US | disclosed |
| US-7329680-B2 | Heterocycle substituted carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2008-02-12 | — | — | US | disclosed |
| EP-1844043-A2 | HETEROCYCLE SUBSTITUTED CARBOXYLIC ACIDS FOR THE TREATMENT OF DIABETES | The Institutes for Pharmaceutical Discovery, LLC (US) | 2007-10-17 | — | — | EP | disclosed |
| US-20060122222-A1 | Heterocycle substituted carboxylic acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC | 2006-06-08 | — | — | US | disclosed |
| WO-2006055708-A2 | HETEROCYCLE SUBSTITUTED CARBOXYLIC ACIDS FOR THE TREATMENT OF DIABETES | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2006-05-26 | — | — | WO | disclosed |
| US-20050004114-A1 | Heterocycle substituted carboxylic acids | INSTITUTE FOR DIABETES DISCOVERY, L.L.C. | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004114-A1 | Heterocycle substituted carboxylic acids | PTPRC, PTPRS, PTPRJ | ALDH1A1 287/4885KDM4E 1427/4885SMN1; SMN2 1400/4885 |
| US-20080146574-A1 | Heterocycle Substituted Carboxylic Acids | PTPRC, PTPRS, PTPRJ | ALDH1A1 287/4885KDM4E 1427/4885SMN1; SMN2 1400/4885 |
| US-20060122222-A1 | Heterocycle substituted carboxylic acids | PTPRC, PTPRS, PTPRJ | ALDH1A1 287/4885KDM4E 1427/4885SMN1; SMN2 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.