Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | WDR5 | P61964 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ENGASE | Q8NFI3 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.42 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9742496 | 0.90 | MAPT (0.42) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL8672723 | 0.83 | MEN1 (0.38) | MAPTNPC1TSHRALDH1A1KMT2A | |
| SCHEMBL8669339 | 0.82 | MEN1 (0.39) | NPC1RAB9ATSHRALDH1A1KMT2A | |
| SCHEMBL8443200 | 0.82 | KMT2A (0.42) | MAPTNPC1RAB9ACYP2C9TSHR | |
| SCHEMBL8550349 | 0.81 | KDM4E (0.42) | MAPTRAB9ATSHRALDH1A1KMT2A | |
| SCHEMBL1559770 | 0.81 | MAPT (0.50) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL1559910 | 0.81 | MAPT (0.50) | MAPTNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL8668968 | 0.79 | SMN1; SMN2 (0.39) | MAPTNPC1RAB9ACYP2C9ALDH1A1 | |
| SCHEMBL8551897 | 0.78 | LMNA (0.35) | MAPTNPC1TSHRKMT2ALMNA | |
| SCHEMBL8672735 | 0.78 | MAPT (0.37) | MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108314675-B | Preparation method of high-optical-purity anti-gastric ulcer drug R-lansoprazole | 浙江药苑生物科技有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-108314675-B | Preparation method of high-optical-purity anti-gastric ulcer drug R-lansoprazole | 浙江药苑生物科技有限公司 | 2020-08-07 | — | — | CN | disclosed |
| WO-2008087665-A2 | PROCESS FOR PREPARATION OF LANSOPRAZOLE | MATRIX LABORATORIES LTD (IN) | 2008-07-24 | — | — | WO | disclosed |
| EP-0585722-B1 | Benzimidazole derivatives as antimicrobal agent against Campylobacter pylon | EISAI CO LTD (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0585722-A1 | Benzimidazole derivatives as antimicrobal agent against Campylobacter pylon | Eisai Co., Ltd. (JP) | 1994-03-09 | — | — | EP | disclosed |