Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672723 | 0.83 | MEN1 (0.38) | MAPTPDPK1KMT2APOLBMEN1 | |
| SCHEMBL8671190 | 0.83 | AR (0.56) | MAPTKMT2APOLBARMEN1 | |
| SCHEMBL8669468 | 0.83 | CYP1A2 (0.44) | MAPTKMT2APOLBMEN1LMNA | |
| SCHEMBL8443200 | 0.82 | KMT2A (0.42) | MAPTKMT2APOLBARMEN1 | |
| SCHEMBL8669339 | 0.82 | MEN1 (0.39) | KMT2APOLBMEN1LMNASMN1; SMN2 | |
| SCHEMBL8550349 | 0.81 | KDM4E (0.42) | MAPTTHRBKMT2APOLBMEN1 | |
| SCHEMBL8668968 | 0.79 | SMN1; SMN2 (0.39) | MAPTGRM2KMT2APOLBAR | |
| SCHEMBL5134227 | 0.78 | MAPT (0.51) | MAPTKMT2ALMNA | |
| SCHEMBL8551897 | 0.78 | LMNA (0.35) | MAPTTHRBKMT2APOLBMEN1 | |
| SCHEMBL8443201 | 0.78 | TDP1 (0.44) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840910-A | Pyridine derivatives having anti-ulcerative activity | ESAI CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |