SCHEMBL5134316

SCHEMBL5134316

NC(=O)Cc1ccc2c(c1)Cc1cc(F)ccc1-2

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
HIF1A Q16665 1/20 0.43
DPP9 Q86TI2 1/20 0.43
CA2 P00918 1/20 0.41
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
AKR1B1 P15121 2/20 0.36
SLC9A1 P19634 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7107209 0.83 CA2 (0.55) CA2RAB9ANPC1MAPTKDM4E
SCHEMBL4422952 0.83 SRD5A2 (0.53) SLC1A3SLC1A2SLC1A1CYP1A2CYP2C9
SCHEMBL577480 0.75 PGR (0.49) SLC1A3SLC1A2SLC1A1CYP1A2CYP2C9
SCHEMBL328637 0.73 CA2 (0.64) CA2
SCHEMBL14711685 0.73 SRD5A1 (0.53) CA2RAB9ANPC1KDM4EALDH1A1
SCHEMBL16526945 0.73 MAPK8 (0.54) CYP1A2CYP2C9CA2MAPTALDH1A1
Hydrochloric Acid SCHEMBL5795470 0.72 CA2 (0.61) CA2
SCHEMBL11812488 0.71 NPC1 (0.56) SLC1A3SLC1A2SLC1A1CYP1A2CYP2C9
SCHEMBL31339549 0.71 MAPK8 (0.55) CYP1A2CYP2C9CA2MAPTALDH1A1
SCHEMBL658778 0.71 MAPK8 (0.55) CYP1A2CYP2C9CA2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7345108-B2 Additives for imparting mar and scratch resistance and compositions comprising the same PPG INDUSTRIES OHIO, INC. (US) 2008-03-18 US disclosed
US-7268176-B2 Additives for imparting mar and scratch resistance and compositions comprising the same PPG INDUSTRIES OHIO, INC. (US) 2007-09-11 US disclosed
US-20060178473-A1 Sulfonamide modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers HU SHENGKUI 2006-08-10 US disclosed
US-7087683-B2 Sulfonamide modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers PPG INDUSTRIES OHIO, INC. (US) 2006-08-08 US disclosed
US-20060078748-A1 Novel additives for imparting Mar and scratch resistance and compositions comprising the same AMBROSE RONALD R 2006-04-13 US disclosed
US-6809161-B2 Storage stable PPG INDUSTRIES OHIO, INC. 2004-10-26 US disclosed
US-6797387-B2 UNGELLED REACTION PRODUCT OF AN AMINOPLAST, A URETHANE GROUP-CONTAINING ADDUCT, WHICH IS A PRODUCT OF AN ISOCYANATE AND A POLYFUNCTIONAL POLYMER, AND AROMATIC, KETONE AND 1,4-DIOXANE DERIVATIVES WITH REACTIVE HYDROGEN GROUPS PPG INDUSTRIES OHIO INC. 2004-09-28 US disclosed
US-6784258-B2 UNGELLED REACTION PRODUCT OF AN AMINOPLAST, A URETHANE GROUP-CONTAINING ADDUCT, WHICH IS A PRODUCT OF AN ISOCYANATE AND A POLYFUNCTIONAL POLYMER, AND AROMATIC, KETONE AND 1,4-DIOXANE DERIVATIVES WITH REACTIVE HYDROGEN GROUPS PPG INDUSTRIES OHIO, INC. 2004-08-31 US disclosed
US-20040116585-A1 Novel additives for imparting mar and scratch resistance and compositions comprising the same PPG INDUSTRIES OHIO, INC. 2004-06-17 US disclosed
EP-1421128-A1 MODIFIED AMINOPLAST CROSSLINKERS AND POWDER COATING COMPOSITIONS CONTAINING SUCH CROSSLINKERS PPG Industries Ohio, Inc. (US) 2004-05-26 EP disclosed
WO-2003011936-A1 MODIFIED AMINOPLAST CROSSLINKERS AND POWDER COATING COMPOSITIONS CONTAINING SUCH CROSSLINKERS PPG INDUSTRIES OHIO, INC. (US) 2003-02-13 WO disclosed
WO-2003011933-A1 MODIFIED AMINOPLAST CROSSLINKERS AND POWDER COATING COMPOSITIONS CONTAINING SUCH CROSSLINKERS PPG INDUSTRIES OHIO, INC (US) 2003-02-13 WO disclosed
WO-2003011970-A1 MODIFIED AMINOPLAST CROSSLINKERS AND POWDER COATING COMPOSITIONS CONTAINING SUCH CROSSLINKERS PPG INDUSTRIES OHIO, INC. (US) 2003-02-13 WO disclosed
WO-2003011932-A1 MODIFIED AMINOPLAST CROSSLINKERS AND POWER COATING COMPOSITIONS CONTAINING SUCH CROSSLINKERS PPG INDUSTRIES OHIO, INC. (US) 2003-02-13 WO disclosed
WO-2003011934-A1 MODIFIED AMINOPLAST CROSSLINKERS AND POWDER COATING COMPOSITIONS CONTAINING SUCH CROSSLINKERS PPG INDUSTRIES OHIO, INC. (US) 2003-02-13 WO disclosed
WO-2003011935-A2 MODIFIED AMINOPLAST CROSSLINKERS AND POWDER COATING COMPOSITIONS CONTAINING SUCH CROSSLINKERS PPG INDUSTRIES OHIO, INC. (US) 2003-02-13 WO disclosed
US-20020132935-A1 Modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers PPG INDUSTRIES OHIO, INC. 2002-09-19 US disclosed
US-20020071955-A1 Modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers PPG INDUSTRIES OHIO, INC. 2002-06-13 US disclosed
US-20020040112-A1 Modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers PPG INDUSTRIES OHIO, INC. 2002-04-04 US disclosed
US-20020037973-A1 Modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers PPG INDUSTRIES OHIO, INC. 2002-03-28 US disclosed