Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.66 |
| ▸ | PDE4A | P27815 | 8/20 | 0.66 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.66 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.66 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | PNP | P00491 | 1/20 | 0.59 |
| ▸ | MPO | P05164 | 3/20 | 0.45 |
| ▸ | TPO | P07202 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351662 | 0.82 | ADORA2A (0.67) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8351660 | 0.82 | ADORA2A (0.67) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7466316 | 0.80 | ADORA2A (1.00) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5515323 | 0.80 | ADORA2A (0.71) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL516503 | 0.77 | ADORA2B (1.00) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10980302 | 0.77 | ADORA2A (0.72) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3699117 | 0.77 | PDE4A (0.73) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| Enprofylline SCHEMBL156402 | 0.77 | PDE4A (1.00) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| Enprofylline SCHEMBL1817246 | 0.77 | PDE4A (1.00) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11215917 | 0.76 | PDE4A (0.43) | ADORA2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960884-B1 | Process for the production of 3,7-dialkylxanthins from 3-alkylxanthins | AVENTIS PHARMA GMBH (DE) | 2002-10-09 | — | — | EP | claimed |
| EP-0811623-B1 | Xanthine derivatives with end-aminated alkynol side chains | HOECHST AG (DE) | 2001-04-04 | — | — | EP | claimed |
| EP-0597377-B1 | Process for the production of 3,7-Dialkylxanthine from 3-Alkylxanthine | AVENTIS PHARMA GMBH (DE) | 2000-08-16 | — | — | EP | claimed |
| US-5475107-A | Process for obtaining 3,7-dialkylxanthines from 3-alkyl-xanthines | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-12-12 | — | — | US | claimed |
| EP-0270305-B1 | SPHEROIDS | Euroceltique S.A. (LU) | 1993-01-20 | — | — | EP | claimed |
| EP-0344960-B1 | CONTROLLED RELEASE DOSAGE FORMS HAVING A DEFINED WATER CONTENT | EURO CELTIQUE SA (LU) | 1992-12-30 | — | — | EP | claimed |
| EP-0502043-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR. | LVMH RECH (FR) | 1992-09-09 | — | — | EP | claimed |
| US-5091189-A | Tablet contains 3-alkylxanthine, hydrophilic or hydrophobic polymers, and wax from the group consists of polyalkylene glycol | EUROCELTIQUE S.A. (LU) | 1992-02-25 | — | — | US | claimed |
| EP-0330031-B1 | THERAPEUTIC AGENTS FOR THE TREATMENT OF PEPTIC ULCER DISEASE | HOECHST JAPAN LIMITED (JP) | 1991-12-11 | — | — | EP | claimed |
| WO-1991007945-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECHERCHE (FR) | 1991-06-13 | — | — | WO | claimed |
| EP-0268585-B1 | TERTIARY HYDROXYALKYLXANTHINES, THEIR MANUFACTURING PROCESS, MEDICINES CONTAINING THEM AND USE THEREOF | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | claimed |
| EP-0344960-A2 | Controlled release dosage forms having a defined water content | Euroceltique S.A. (LU) | 1989-12-06 | — | — | EP | claimed |
| EP-0330031-A1 | Therapeutic agents for the treatment of peptic ulcer disease | HOECHST JAPAN LIMITED (JP) | 1989-08-30 | — | — | EP | claimed |
| US-4844910-A | CONTROLLED RELEASE OF THEOPHYLLINE DERIVATIVES | EUROCELTIQUE, S.A. (LU) | 1989-07-04 | — | — | US | claimed |
| EP-0270305-A2 | Spheroids | Euroceltique S.A. (LU) | 1988-06-08 | — | — | EP | claimed |
| EP-0268585-A1 | TERTIARY HYDROXYALKYLXANTHINES, THEIR MANUFACTURING PROCESS, MEDICINES CONTAINING THEM AND USE THEREOF. | HOECHST AG (DE) | 1988-06-01 | — | — | EP | claimed |
| WO-1987000523-A2 | TERTIARY HYDROXYALKYLXANTHINES, THEIR MANUFACTURING PROCESS, MEDICINES CONTAINING THEM AND USE THEREOF | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-01-29 | — | — | WO | claimed |
| JP-6192260-A | — | — | None | — | — | JP | disclosed |
| EP-0010531-A1 | 3-Alkylxanthines, processes for their preparation and compositions for use in the treatment of chronic obstructive airway disease and cardiac disease | Aktiebolaget DRACO (SE) | 1980-04-30 | — | — | EP | disclosed |
| EP-0010531-A1 | 3-Alkylxanthines, processes for their preparation and compositions for use in the treatment of chronic obstructive airway disease and cardiac disease | Aktiebolaget DRACO (SE) | 1980-04-30 | — | — | EP | disclosed |