Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5183524 | 0.85 | PDE5A (0.41) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL4623642 | 0.82 | ALDH1A1 (0.41) | MEN1KMT2AADORA2BADORA3ALDH1A1 | |
| SCHEMBL18039294 | 0.82 | ADORA2B (0.40) | PDE4APDE4BPDE4CPDE4DADORA2B | |
| SCHEMBL8947982 | 0.81 | POLB (0.40) | ADORA2BADORA3ALDH1A1ADORA2APOLB | |
| SCHEMBL6755794 | 0.78 | ADORA2B (0.38) | ADORA2BADORA3ALDH1A1ADORA2APOLB | |
| SCHEMBL18036533 | 0.76 | ADORA2B (0.38) | MEN1KMT2AADORA2BADORA3ALDH1A1 | |
| SCHEMBL5134359 | 0.76 | ADORA2A (0.66) | PDE4APDE4BPDE4CPDE4DPNP | |
| SCHEMBL11591427 | 0.76 | ADORA2B (0.57) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7345938 | 0.75 | PDE5A (0.66) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL4551932 | 0.75 | TRAP1 (0.54) | ADORA2BADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4397779-A | RADIOIMMUNOASSAY OF THEOPHYLLINE AND DERIVATIVES; IODINATION | BAXTER TRAVENOL LABORATORIES, INC. (US) | 1983-08-09 | — | — | US | disclosed |
| US-4297494-A | Xanthine tracers | BAXTER TRAVENOL LABORATORIES, INC. (US) | 1981-10-27 | — | — | US | disclosed |