Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | MMP9 | P14780 | 4/20 | 0.53 |
| ▸ | MMP8 | P22894 | 4/20 | 0.53 |
| ▸ | MMP13 | P45452 | 4/20 | 0.53 |
| ▸ | MMP12 | P39900 | 3/20 | 0.53 |
| ▸ | MMP14 | P50281 | 3/20 | 0.53 |
| ▸ | MMP16 | P51512 | 3/20 | 0.53 |
| ▸ | MMP1 | P03956 | 2/20 | 0.53 |
| ▸ | MMP3 | P08254 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505289 | 0.87 | MMP2 (0.58) | MMP2MMP9MMP8MMP13MMP12 | |
| SCHEMBL31061277 | 0.85 | HTR2A (0.51) | MMP2MMP9MMP8MMP13MMP12 | |
| SCHEMBL7191147 | 0.84 | POLB (0.58) | MMP2MMP9MMP8MMP13MMP12 | |
| SCHEMBL17331336 | 0.84 | MEN1 (0.46) | MMP2MMP9MMP8MMP13MMP12 | |
| SCHEMBL29046725 | 0.83 | MMP2 (0.56) | MMP2MMP9MMP8MMP13MMP12 | |
| SCHEMBL13908249 | 0.83 | MMP2 (0.53) | MMP2MMP9MMP8MMP13MMP12 | |
| SCHEMBL28718433 | 0.82 | MMP2 (0.49) | MMP2MMP9MMP8MMP13MMP12 | |
| SCHEMBL10595756 | 0.81 | TSHR (0.50) | MMP2MMP9MMP8MMP13MMP1 | |
| SCHEMBL10670726 | 0.81 | KIF18A (0.55) | ALDH1A1MAPK1CA1CA2MAPT | |
| SCHEMBL27480676 | 0.81 | KIF18A (0.51) | ALDH1A1CA1CA2CCR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976536-A2 | BORON-CONTAINING SMALL MOLECULES | Anacor Pharmaceuticals, Inc. (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007078340-A2 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2007-07-12 | — | — | WO | disclosed |