Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.31 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5146834 | 0.72 | KMT2A (0.32) | — | |
| SCHEMBL5190879 | 0.72 | IRAK4 (0.36) | PARP1BTK | |
| SCHEMBL5134855 | 0.66 | OPRL1 (0.34) | BTKOPRL1 | |
| SCHEMBL5136172 | 0.66 | IRAK4 (0.38) | PARP1 | |
| SCHEMBL5134806 | 0.65 | PARP2 (0.39) | PARP1BTK | |
| SCHEMBL5135452 | 0.59 | SLC6A4 (0.47) | PARP1EZH2 | |
| SCHEMBL14168394 | 0.58 | POLB (0.44) | — | |
| SCHEMBL11044013 | 0.58 | TAS1R3 (0.45) | — | |
| SCHEMBL17185049 | 0.58 | PARP1 (0.46) | PARP1 | |
| SCHEMBL2311682 | 0.57 | TAS1R3 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942893-A2 | PIPERIDINE GLYCINE TRANSPORTER INHIBITORS | Merck & Co., Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007053400-A2 | PIPERIDINE GLYCINE TRANSPORTER INHIBITORS | MERCK & CO., INC. (US) | 2007-05-10 | — | — | WO | disclosed |