Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140943 | 0.86 | STAT3 (0.43) | KMT2A | |
| SCHEMBL140930 | 0.74 | MMP2 (0.47) | KMT2A | |
| SCHEMBL28996978 | 0.74 | ENPP2 (0.46) | ENPP2PTGS2PTGS1 | |
| Magnesium SCHEMBL30746780 | 0.72 | ENPP2 (0.45) | ENPP2PTGS2PTGS1 | |
| Hydrochloric Acid SCHEMBL29163882 | 0.72 | ENPP2 (0.45) | ENPP2PTGS2GSRPTGS1 | |
| SCHEMBL23703227 | 0.71 | GAA (0.43) | KMT2A | |
| SCHEMBL3149080 | 0.70 | CA2 (0.47) | KMT2A | |
| SCHEMBL14390991 | 0.70 | STAT3 (0.42) | KMT2A | |
| SCHEMBL8763931 | 0.70 | SMN1; SMN2 (0.40) | KMT2A | |
| Butane SCHEMBL15941687 | 0.70 | MMP2 (0.44) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891080-A2 | NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS | Metabasis Therapeutics, Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006128055-A2 | NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS | METABASIS THERAPEUTICS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |