Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5012713 | 0.83 | PIK3R1 (0.35) | KDM4EHTTPIK3R1PIK3CAMTOR | |
| SCHEMBL5133875 | 0.81 | PIK3R1 (0.34) | KDM4EHTTPIK3R1PIK3CAMTOR | |
| SCHEMBL5012716 | 0.81 | PIK3R1 (0.34) | KDM4EHTTPIK3R1PIK3CAMTOR | |
| SCHEMBL5066596 | 0.80 | HTT (0.34) | KDM4EHTTHPGDALDH1A1 | |
| SCHEMBL5015657 | 0.80 | PIK3R1 (0.34) | KDM4EHTTPIK3R1PIK3CAMTOR | |
| SCHEMBL5014333 | 0.80 | PIK3R1 (0.36) | KDM4EHTTPIK3R1PIK3CAMTOR | |
| SCHEMBL5012742 | 0.80 | PIK3R1 (0.34) | KDM4EHTTPIK3R1PIK3CAMTOR | |
| SCHEMBL5015619 | 0.80 | HRH3 (0.37) | KDM4EHTTPIK3R1PIK3CAMTOR | |
| SCHEMBL5014366 | 0.79 | ALDH1A1 (0.43) | KDM4EHTTPIK3R1PIK3CAMTOR | |
| SCHEMBL5012668 | 0.78 | HTT (0.34) | KDM4EHTTPIK3R1PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888597-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006120563-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-11-16 | — | — | WO | disclosed |