Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 10/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934649 | 1.00 | CXCR4 (0.55) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL29223244 | 0.98 | CXCR4 (0.52) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL935078 | 0.96 | SIGMAR1 (0.50) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL2916592 | 0.96 | SIGMAR1 (0.50) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL24177173 | 0.94 | SIGMAR1 (0.49) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL13805257 | 0.92 | SIGMAR1 (0.48) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL28997961 | 0.92 | CHRM5 (0.47) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL22398868 | 0.91 | SIGMAR1 (0.46) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL8675042 | 0.90 | CHRM5 (0.49) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| Pyrrolidine SCHEMBL4661508 | 0.90 | CHRM5 (0.52) | CXCR4MEN1CHRM2CHRM1ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080299137-A1 | Fusion Proteins That Bind Effector Lymphocytes And Target Cells | NOVO NORDISK A/S (DK) | 2008-12-04 | — | — | US | disclosed |