SCHEMBL934649

SCHEMBL934649

O=C(O)CN1CCCNCCNCCCNCC1

nearest known ligand 0.77

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 10/20 0.55
MEN1 O00255 1/20 0.49
CHRM2 P08172 1/20 0.49
CHRM1 P11229 1/20 0.49
ADRA2C P18825 1/20 0.49
CCR2 P41597 1/20 0.49
CXCL12 P48061 1/20 0.49
BLM P54132 1/20 0.49
KMT2A Q03164 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
HRH3 Q9Y5N1 1/20 0.49
SIGMAR1 Q99720 3/20 0.48
CHRM5 P08912 2/20 0.47
CHRM3 P20309 2/20 0.47
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5134779 1.00 CXCR4 (0.55) CXCR4MEN1CHRM2CHRM1ADRA2C
SCHEMBL29223244 0.98 CXCR4 (0.52) CXCR4MEN1CHRM2CHRM1ADRA2C
SCHEMBL935078 0.96 SIGMAR1 (0.50) CXCR4MEN1CHRM2CHRM1ADRA2C
SCHEMBL2916592 0.96 SIGMAR1 (0.50) CXCR4MEN1CHRM2CHRM1ADRA2C
SCHEMBL24177173 0.94 SIGMAR1 (0.49) CXCR4MEN1CHRM2CHRM1ADRA2C
SCHEMBL13805257 0.92 SIGMAR1 (0.48) CXCR4MEN1CHRM2CHRM1ADRA2C
SCHEMBL28997961 0.92 CHRM5 (0.47) CXCR4MEN1CHRM2CHRM1ADRA2C
SCHEMBL22398868 0.91 SIGMAR1 (0.46) CXCR4MEN1CHRM2CHRM1ADRA2C
SCHEMBL8675042 0.90 CHRM5 (0.49) CXCR4MEN1CHRM2CHRM1ADRA2C
Pyrrolidine SCHEMBL4661508 0.90 CHRM5 (0.52) CXCR4MEN1CHRM2CHRM1ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719486-A1 CONJUGATES AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
EP-4719498-A1 RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
WO-2025199636-A1 TARGETED RADIOLIGAND COMPOUNDS AND USES THEREOF MCMASTER UNIVERSITY (CA) 2025-10-02 WO claimed
EP-4619411-A1 DUAL RECEPTOR TARGETING RADIOLIGANDS AND USES THEREOF Full-Life Technologies HK Limited (HK) 2025-09-24 EP claimed
EP-4556029-A2 RADIOPHARMACEUTICAL CONJUGATE The South African Nuclear Energy Corporation Limited (ZA) 2025-05-21 EP claimed
US-20250099632-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF FULL-LIFE TECHNOLOGIES UK LIMITED (GB) 2025-03-27 US claimed
US-20250026739-A1 COMPOUNDS AND RADIOLIGANDS FOR TARGETING NEUROTENSIN RECEPTOR AND USES THEREOF FULL-LIFE TECHNOLOGIES HK LIMITED (CN) 2025-01-23 US claimed
EP-4479040-A1 COMPOUNDS AND RADIOLIGANDS FOR TARGETING NEUROTENSIN RECEPTOR AND USES THEREOF Full-Life Technologies HK Limited (HK) 2024-12-25 EP claimed
WO-2024245421-A1 RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF FULL-LIFE TECHNOLOGIES HK LIMITED (CN) 2024-12-05 WO claimed
WO-2024245407-A1 CONJUGATES AND USES THEREOF FULL-LIFE TECHNOLOGIES HK LIMITED (CN) 2024-12-05 WO claimed
US-20190175750-A1 COMPOSITION AND METHOD FOR MODIFYING POLYPEPTIDES ADVANCED PROTEOME THERAPEUTICS INC. 2019-06-13 US claimed
EP-2453927-B1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES UNIV DENMARK TECH DTU (DK) 2019-05-15 EP claimed
EP-2651447-B1 ENTRAPMENT OF RADIONUCLIDES IN NANOPARTICLE COMPOSITIONS UNIV DENMARK TECH DTU (DK) 2018-08-29 EP claimed
US-20170296684-A1 RADIOPHARMACEUTICAL CONJUGATE UNIVERSITY OF CAPE TOWN (ZA) 2017-10-19 US claimed
US-20160158392-A1 Entrapment of Radionuclides in Nanoparticle Compositions RIGSHOSPITALET (DK) 2016-06-09 US claimed
US-9226984-B2 Entrapment of radionuclides in nanoparticle compositions Technical University of Denmark and Rigshospitalet (DK) 2016-01-05 US claimed
US-8920775-B2 Loading technique for preparing radionuclide containing nanoparticles TECHNICAL UNIVERSITY OF DENMARK (DK) 2014-12-30 US claimed
US-20130251630-A1 Entrapment of Radionuclides in Nanoparticle Compositions RIGSHOSPITALET (DK) 2013-09-26 US claimed
US-20120213698-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES RIGSHOSPITALET (DK) 2012-08-23 US claimed
EP-2453927-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES Technical University of Denmark (DK) 2012-05-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250026739-A1 COMPOUNDS AND RADIOLIGANDS FOR TARGETING NEUROTENSIN RECEPTOR AND USES THEREOF NTSR1, NTSR2, NPSR1 CXCR4 447/4885MEN1 281/4885CHRM2 835/4885
US-20250099632-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF ASGR1, GNRHR, SCTR CXCR4 641/4885MEN1 842/4885CHRM2 1767/4885
US-20190175750-A1 COMPOSITION AND METHOD FOR MODIFYING POLYPEPTIDES PTMS, SRMS, ACP1 CXCR4 1899/4885MEN1 1660/4885CHRM2 3509/4885
US-20120213698-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES LIPG, NPC1L1, CD47 CXCR4 790/4885MEN1 154/4885CHRM2 4748/4885
US-20170296684-A1 RADIOPHARMACEUTICAL CONJUGATE FOLH1, EPRS1, FOLR1 CXCR4 571/4885MEN1 244/4885CHRM2 2386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.