SCHEMBL513490

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1854417	0.85	ALDH1A1 (0.61)	ALDH1A1SMN1; SMN2GAAMAPK1MAPT
	SCHEMBL7870367	0.83	ALDH1A1 (0.56)	ALDH1A1SMN1; SMN2GAAMAPK1MAPT
	SCHEMBL380709	0.81	ALDH1A1 (0.57)	ALDH1A1SMN1; SMN2GAAMAPK1MAPT
	SCHEMBL8751720	0.81	ALDH1A1 (0.57)	ALDH1A1SMN1; SMN2GAAMAPTL3MBTL1
	SCHEMBL11002701	0.80	ALDH1A1 (0.55)	ALDH1A1SMN1; SMN2GAAMAPK1MAPT
	SCHEMBL7876880	0.80	ALDH1A1 (0.56)	ALDH1A1SMN1; SMN2GAAMAPK1MAPT
	SCHEMBL1532324	0.79	ALDH1A1 (0.58)	ALDH1A1SMN1; SMN2GAAMAPK1MAPT
	SCHEMBL2103568	0.79	MAPK1 (0.55)	ALDH1A1SMN1; SMN2GAAMAPK1MAPT
	SCHEMBL12047925	0.78	ALDH1A1 (0.89)	ALDH1A1SMN1; SMN2GAAL3MBTL1TDP1
	SCHEMBL7878478	0.78	ALDH1A1 (0.55)	ALDH1A1SMN1; SMN2GAAMAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.