SCHEMBL7870367

SCHEMBL7870367

CN(C(=O)OCI)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
GAA P10253 3/20 0.49
MAPT P10636 2/20 0.44
L3MBTL1 Q9Y468 3/20 0.43
MAPK1 P28482 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
PHLPP2 Q6ZVD8 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ATM Q13315 3/20 0.41
MMP14 P50281 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8751720 0.86 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2GAAMAPTL3MBTL1
SCHEMBL7876880 0.85 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2GAAMAPTL3MBTL1
SCHEMBL513490 0.83 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2GAAMAPTL3MBTL1
SCHEMBL28032524 0.81 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2GAAMAPTL3MBTL1
SCHEMBL1854417 0.81 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2GAAMAPTL3MBTL1
SCHEMBL4459679 0.80 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2GAAMAPTL3MBTL1
SCHEMBL11002701 0.80 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2GAAMAPTL3MBTL1
SCHEMBL4467320 0.79 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2GAAMAPTL3MBTL1
SCHEMBL10759692 0.78 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2GAAMAPTL3MBTL1
SCHEMBL380709 0.77 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2GAAMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001056358-A2 ENHANCED PROPERTIED PESTICIDES ROHM AND HAAS COMPANY (US) 2001-08-09 WO disclosed