SCHEMBL513566

SCHEMBL513566

C[Si](C)(CCC(=O)O)O[Si](C)(C)CCC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.41
LMNA P02545 4/20 0.40
EGLN1 Q9GZT9 2/20 0.40
ALKBH5 Q6P6C2 1/20 0.40
SUCNR1 Q9BXA5 1/20 0.40
FFAR3 O14843 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
SLC15A2 Q16348 1/20 0.38
SLC22A6 Q4U2R8 2/20 0.36
NFKB1 P19838 1/20 0.35
PMP22 Q01453 1/20 0.35
AKR1B1 P15121 1/20 0.35
ALDH1A1 P00352 3/20 0.34
KDM6B O15054 1/20 0.34
KDM5C P41229 1/20 0.34
PHF8 Q9UPP1 1/20 0.34
KDM2A Q9Y2K7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11148349 0.97 TSHR (0.39) TSHRLMNAEGLN1ALKBH5SUCNR1
SCHEMBL4967244 0.90 TSHR (0.38) TSHRLMNAEGLN1ALKBH5SUCNR1
SCHEMBL29005749 0.87 CAMK2A (0.44) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL512941 0.85 TSHR (0.48) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL23908692 0.83 LMNA (0.50) TSHRLMNASLC22A6NFKB1PMP22
Hydrochloric Acid SCHEMBL7534254 0.83 TSHR (0.46) TSHRLMNASLC22A6NFKB1PMP22
Hydrochloric Acid SCHEMBL5368847 0.83 TSHR (0.46) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL26606104 0.83 LMNA (0.44) TSHRLMNAEGLN1ALKBH5SUCNR1
SCHEMBL20127165 0.82 TSHR (0.31) TSHR
SCHEMBL3806081 0.82 TSHR (0.44) TSHRLMNAEGLN1ALKBH5SUCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118026778-A Functional water-soluble fertilizer containing humic acid and preparation method thereof 河北上桥生物科技有限公司 2024-05-14 CN claimed
CN-118026778-A Functional water-soluble fertilizer containing humic acid and preparation method thereof 河北上桥生物科技有限公司 2024-05-14 CN disclosed
CN-118026778-A Functional water-soluble fertilizer containing humic acid and preparation method thereof 河北上桥生物科技有限公司 2024-05-14 CN disclosed
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed
CN-111378138-A Combined energy absorption method and application thereof 翁秋梅 2020-07-07 CN disclosed
CN-111040203-A Energy absorption method based on hybrid cross-linked dynamic polymer 翁秋梅 2020-04-21 CN disclosed
CN-111040202-A Combined hybrid dynamic polymer and application thereof 翁秋梅 2020-04-21 CN disclosed
EP-2598589-B1 A COMPOSITION FOR COATING OVER A PHOTORESIST PATTERN MERCK PATENT GMBH (DE) 2019-05-22 EP disclosed
US-8852848-B2 Composition for coating over a photoresist pattern Z Electronic Materials USA Corp. (US) 2014-10-07 US disclosed
US-6331275-B1 DIAGNOSTICS AND THE DETECTION OF SMALL QUANTITIES OF SUBSTANCES IN FLUIDS; USED FOR MULTIPLE QUANTITATIVE ASSAYS, AND PREFERABLY REQUIRING NO SPECIALIZED DETECTOR INSTRUMENTATION. BURSTEIN TECHNOLOGIES, INC. 2001-12-18 US disclosed
US-6312901-B2 A CLEAVABLE SPACER ELEMENT WITH A SUBSTRATE ATTACHING END AND A SIGNAL RESPONSIVE END; BINDING ANALYTES TO THE CLEAVABLE SIGNAL ELEMENT TETHERS THE SIGNAL RESPONSIVE MOIETY TO THE SIGNAL ELEMENT'S SUBSTRATE END; DIGITAL VIDEO DISC DETECTION BURSTEIN TECHNOLOGIES, INC. 2001-11-06 US disclosed
US-20010016316-A1 SPATIALLY ADDRESSABLE, CLEAVABLE REFLECTIVE SIGNAL ELEMENTS, ASSAY DEVICE AND METHOD VINDUR TECHNOLOGIES, INC. (NO) 2001-08-23 US disclosed
EP-1097378-A2 OPTICAL DISC-BASED ASSAY DEVICES AND METHODS Burstein Laboratories Inc. (US) 2001-05-09 EP disclosed
EP-0918845-A4 CLEAVABLE SIGNAL ELEMENT DEVICE AND METHOD BURSTEIN LAB INC (US) 2000-08-30 EP disclosed
WO-2000005582-A2 OPTICAL DISC-BASED ASSAY DEVICES AND METHODS BURSTEIN LABORATORIES, INC. (US) 2000-02-03 WO disclosed
EP-0918845-A1 CLEAVABLE SIGNAL ELEMENT DEVICE AND METHOD BURSTEIN LABORATORIES, INC. (US) 1999-06-02 EP disclosed
WO-1998001533-A1 CLEAVABLE SIGNAL ELEMENT DEVICE AND METHOD BURSTEIN LABORATORIES, INC. (US) 1998-01-15 WO disclosed
EP-0022056-B1 DIMERS OF TRI-IODATED ISOPHTHALIC ACID DIAMIDES, THEIR PREPARATION, X-RAY CONTRAST AGENT CONTAINING THEM, AND DIMER OF TRI-IODATED ISOPHTHALIC ACID CHLORIDE SCHERING AKTIENGESELLSCHAFT (DE) 1983-06-29 EP disclosed
EP-0022056-A2 Dimers of tri-iodated isophthalic acid diamides, their preparation, X-ray contrast agent containing them, and dimer of tri-iodated isophthalic acid chloride SCHERING AKTIENGESELLSCHAFT (DE) 1981-01-07 EP disclosed