Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL513566 | 0.90 | TSHR (0.41) | TSHRLMNAEGLN1ALKBH5SUCNR1 | |
| Hydrochloric Acid SCHEMBL11148349 | 0.88 | TSHR (0.39) | TSHRLMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL8674170 | 0.85 | LMNA (0.46) | TSHRLMNASLC22A6ALDH1A1AKR1B1 | |
| SCHEMBL526437 | 0.81 | LMNA (0.36) | TSHRLMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL30612730 | 0.81 | LMNA (0.36) | TSHRLMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL30612731 | 0.81 | LMNA (0.36) | TSHRLMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL13051353 | 0.81 | ALDH1A1 (0.41) | TSHRLMNASLC15A2ALDH1A1 | |
| SCHEMBL17035392 | 0.80 | TSHR (0.44) | TSHRLMNASLC22A6ALDH1A1NFKB1 | |
| SCHEMBL1581340 | 0.79 | TET2 (0.31) | — | |
| SCHEMBL29005749 | 0.79 | CAMK2A (0.44) | TSHRLMNASLC22A6ALDH1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968642-A2 | KERATIN-BINDING EFFECTOR MOLECULES AND METHOD FOR THE PRODUCTION THEREOF BY COUPLING KERATIN-BINDING POLYPEPTIDES WITH EFFECTOR MOLECULES WHICH SUPPORT CARBOXYLIC GROUPS OR SULFONIC ACID GROUPS | BASF SE (DE) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007060116-A2 | KERATIN-BINDING EFFECTOR MOLECULES AND METHOD FOR THE PRODUCTION THEREOF BY COUPLING KERATIN-BINDING POLYPEPTIDES WITH EFFECTOR MOLECULES THAT SUPPORT CARBOXYLIC GROUPS OR SULFONIC ACID GROUPS | BASF SE (DE) | 2007-05-31 | — | — | WO | disclosed |
| US-4247674-A | Use of bis(fluoroaliphaticsulfonyl)imides in polymerization of organocyclosiloxanes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1981-01-27 | — | — | US | disclosed |