Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6075649 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL1031402 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL6075225 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL14506177 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL10468251 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL7318244 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL7311249 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL10676652 | 0.82 | L3MBTL1 (0.52) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL9204606 | 0.82 | ALDH1A1 (0.63) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL10675878 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942895-A1 | COMBINATION DRUG CONTAINING PROBUCOL AND A TETRAZOLYLALKOXY-DIHYDROCARBOSTYRIL DERIVATIVE WITH SUPEROXIDE SUPRESSANT EFFECTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007032557-A1 | COMBINATION DRUG CONTAINING PROBUCOL AND A TETRAZOLYLALKOXY-DIHYDROCARBOSTYRIL DERIVATIVE WITH SUPEROXIDE SUPRESSANT EFFECTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-22 | — | — | WO | disclosed |