Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318244 | 0.95 | ALDH1A1 (0.56) | ALDH1A1MAPTTP53TSHRPDE3B | |
| SCHEMBL5135783 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTTP53TSHRPDE3B | |
| SCHEMBL6075649 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTTP53TSHRPDE3B | |
| SCHEMBL6075225 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTTP53TSHRPDE3B | |
| SCHEMBL14506177 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTTP53TSHRPDE3B | |
| SCHEMBL10468251 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTTP53TSHRPDE3B | |
| SCHEMBL7311249 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTTP53TSHRPDE3B | |
| SCHEMBL3091610 | 0.82 | ALDH1A1 (0.63) | ALDH1A1MAPTTP53TSHRNPSR1 | |
| SCHEMBL10676652 | 0.80 | L3MBTL1 (0.52) | ALDH1A1MAPTTP53TSHRPDE3B | |
| SCHEMBL9204714 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTTP53TSHRPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105879-A | Synthesis method of 5- (4-chlorobutyl) -1-cyclohexyl-1, 2,3, 4-tetrazole | 河北科技大学 | 2023-11-24 | — | — | CN | claimed |
| CN-111233777-A | Synthesis method of N-cyclohexyl-5- (4-chlorobutyl) -1H-tetrazole | 上海立科药物化学有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-109776498-B | Preparation method of cilostazol | 浙江永宁药业股份有限公司 | 2020-04-07 | — | — | CN | claimed |
| CN-110685047-A | High-elasticity sewing thread | 佛山金丝路线业有限公司 | 2020-01-14 | — | — | CN | claimed |
| CN-107325078-B | Preparation method of cilostazol | 烟台万润药业有限公司 | 2020-01-07 | — | — | CN | claimed |
| CN-107382970-A | A kind of synthetic method of Cilostazol | 浙江金立源药业有限公司 | 2017-11-24 | — | — | CN | claimed |
| CN-105111190-B | A kind of synthetic method of Cilostazol | 浙江金立源药业有限公司 | 2017-11-07 | — | — | CN | claimed |
| CN-107325078-A | A kind of preparation method of Cilostazol | 烟台万润药业有限公司 | 2017-11-07 | — | — | CN | claimed |
| CN-105111190-A | Method for synthesizing cilostazol | ZHEJIANG KINGLYUAN PHARMACEUTICAL COMPANY LTD | 2015-12-02 | — | — | CN | claimed |
| US-7825251-B2 | Process for producing carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-11-02 | — | — | US | claimed |
| CN-1733743-A | N-cyclohexyl-5-(4-chlorobutyl)-1H-tetrazole synthesis method | SHANGHAI RECORD PHARMACEUTICAL (CN) | 2006-02-15 | — | — | CN | claimed |
| US-20050222202-A1 | Highly pure cilostazol and an improved process for obtaining same | PERRIGO API LTD. (IL) | 2005-10-06 | — | — | US | claimed |
| US-20050101631-A1 | Process for producing carbostyril derivatives | OTSUKA PHARMACEUTICALS COMPANY | 2005-05-12 | — | — | US | claimed |
| EP-1311485-A4 | PROCESSES FOR PREPARING CILOSTAZOL | TEVA PHARMA (IL) | 2004-05-12 | — | — | EP | claimed |
| US-20040059117-A1 | Process for producing carbostyril derivatives | OTSUKA PHARMACEUTICALS COMPANY | 2004-03-25 | — | — | US | claimed |
| CN-1469864-A | Process for preparing cilostazol | ������ҩ��ҵ����˾ | 2004-01-21 | — | — | CN | claimed |
| EP-1311485-A1 | PROCESSES FOR PREPARING CILOSTAZOL | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-05-21 | — | — | EP | claimed |
| US-6515128-B2 | Dissolving 6-hydroxy-3,4-dihydroquinolinone and a base in water; dissolving a 1-cyclohexyl-5- (4-halobutyl)-tetrazole in water-immiscible solvent, mixing aqueous phase and organic phase in presence of phase transfer catalyst; recovering | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-02-04 | — | — | US | claimed |
| US-20020099213-A1 | Processes for preparing cilostazol | TEVA PHARMACEUTICALS USA, INC. | 2002-07-25 | — | — | US | claimed |
| WO-2002014283-A1 | PROCESSES FOR PREPARING CILOSTAZOL | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2002-02-21 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222202-A1 | Highly pure cilostazol and an improved process for obtaining same | PDE7A, PDE8B, PDE9A | ALDH1A1 1905/4885MAPT 4246/4885TP53 4592/4885 |
| US-20040059117-A1 | Process for producing carbostyril derivatives | PTGIR, PTGIS, F2R | ALDH1A1 670/4885MAPT 2081/4885TP53 4834/4885 |
| US-20020099213-A1 | Processes for preparing cilostazol | PDE3A, PDE12, PDE5A | ALDH1A1 2070/4885MAPT 3372/4885TP53 4384/4885 |
| US-20050101631-A1 | Process for producing carbostyril derivatives | PTGIR, PTGIS, PLAT | ALDH1A1 1969/4885MAPT 1693/4885TP53 4820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.