Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16394775 | 0.84 | LMNA (0.39) | ALDH1A1KDM4EUSP2LMNAMMP9 | |
| SCHEMBL3597828 | 0.84 | NPSR1 (0.48) | ALDH1A1KDM4EUSP2LMNAMMP9 | |
| SCHEMBL3583043 | 0.79 | NPSR1 (0.47) | ALDH1A1KDM4EUSP2LMNAMMP9 | |
| SCHEMBL18802703 | 0.79 | LIPG (0.37) | ALDH1A1TSHRHSD11B1P2RX4HDAC1 | |
| SCHEMBL18802702 | 0.79 | LIPG (0.41) | ALDH1A1TSHRHSD11B1HDAC1HDAC8 | |
| SCHEMBL18802747 | 0.77 | LIPG (0.44) | ALDH1A1TSHRHDAC1HDAC8MGLL | |
| SCHEMBL18802745 | 0.77 | LIPG (0.44) | ALDH1A1TSHRHDAC1HDAC8MGLL | |
| SCHEMBL4060193 | 0.75 | ALDH1A1 (0.45) | ALDH1A1KDM4EUSP2LMNAMMP9 | |
| SCHEMBL16394966 | 0.75 | KDM4E (0.45) | ALDH1A1KDM4EUSP2LMNAMMP9 | |
| SCHEMBL3578553 | 0.75 | LMNA (0.45) | ALDH1A1KDM4EUSP2LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986649-A2 | NOVEL POLYMORPHS OF MONTELUKAST AMMONIUM SALTS AND PROCESSES FOR PREPARATION THEREFOR | CHEMAGIS LTD. (IL) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007096875-A2 | NOVEL POLYMORPHS OF MONTELUKAST AMMONIUM SALTS AND PROCESSES FOR PREPARATION THEREFOR | CHEMAGIS LTD. (IL) | 2007-08-30 | — | — | WO | disclosed |