Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235426 | 0.81 | SLC6A3 (0.39) | GAACYP3A4TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL595610 | 0.79 | GAA (0.43) | GAACYP3A4TSHRALDH1A1MAPT | |
| SCHEMBL1748176 | 0.77 | GAA (0.40) | GAACYP3A4ALDH1A1MAPTLMNA | |
| SCHEMBL9733426 | 0.73 | GAA (0.66) | GAAALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL12121918 | 0.73 | GSK3B (0.48) | GAAALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL1748024 | 0.73 | GSK3B (0.48) | GAAALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL2763360 | 0.73 | CYP3A4 (0.44) | CYP3A4TSHRALDH1A1MAPTLMNA | |
| SCHEMBL380738 | 0.73 | SRC (0.53) | GAACYP3A4TSHRALDH1A1MAPT | |
| SCHEMBL1747913 | 0.72 | ALDH1A1 (0.45) | GAACYP3A4TSHRALDH1A1MAPT | |
| SCHEMBL1747936 | 0.71 | ALDH1A1 (0.51) | GAACYP3A4TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874317-A2 | PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | Bayer Pharmaceuticals Corporation (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006113919-A2 | ARYL ALKYL ACID DERIVATIVES FOR AND USE THEREOF | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-10-26 | — | — | WO | disclosed |