Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.45 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099153 | 0.94 | KMT2A (0.53) | KMT2ANPSR1KDM4EMAPTHPGD | |
| SCHEMBL3069120 | 0.85 | L3MBTL3 (0.67) | KMT2ANPSR1KDM4EMAPTHPGD | |
| SCHEMBL6843065 | 0.83 | KMT2A (0.70) | KMT2ANPSR1KDM4EMAPTHPGD | |
| SCHEMBL5136397 | 0.83 | KMT2A (0.46) | KMT2ANPSR1KDM4EMAPTHPGD | |
| SCHEMBL3263017 | 0.82 | L3MBTL3 (0.72) | KMT2ANPSR1KDM4EMAPTHPGD | |
| SCHEMBL692922 | 0.82 | MAOB (0.71) | KMT2ANPSR1KDM4EHPGDL3MBTL3 | |
| SCHEMBL493765 | 0.82 | ALDH1A1 (0.63) | KMT2ANPSR1KDM4EMAPTHPGD | |
| SCHEMBL3764746 | 0.81 | CACNA2D1 (0.55) | KMT2ANPSR1KDM4EALDH1A1MAOB | |
| SCHEMBL3766753 | 0.81 | KMT2A (0.51) | KMT2ANPSR1KDM4EMAPTHPGD | |
| SCHEMBL3772656 | 0.81 | ALDH1A1 (0.74) | KMT2ANPSR1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899318-A1 | NEW AZETIDINE DERIVATIVES AS NEUROKININ RECEPTOR ANTAGONISTS FOR THE TREATMENT OF GASTROINTESTINAL DISEASES | AstraZeneca AB (SE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2006137791-A1 | NEW AZETIDINE DERIVATIVES AS NEUROKININ RECEPTOR ANTAGONISTS FOR THE TREATMENT OF GASTROINTESTINAL DISEASES | ASTRAZENECA AB (SE) | 2006-12-28 | — | — | WO | disclosed |