SCHEMBL513681

SCHEMBL513681

O=C(O)CCCCS(=O)(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
TSHR P16473 4/20 0.55
NFKB1 P19838 2/20 0.55
PMP22 Q01453 1/20 0.55
SLC22A6 Q4U2R8 2/20 0.50
APEX1 P27695 1/20 0.48
GPR84 Q9NQS5 4/20 0.46
FFAR1 O14842 2/20 0.46
FFAR4 Q5NUL3 2/20 0.46
APP P05067 1/20 0.46
AKR1B1 P15121 1/20 0.46
CYP2D6 P10635 1/20 0.46
FOLH1 Q04609 1/20 0.46
PRMT1 Q99873 1/20 0.44
PPARG P37231 4/20 0.44
PPARD Q03181 4/20 0.44
PPARA Q07869 4/20 0.44
HDAC11 Q96DB2 3/20 0.44
ALDH1A1 P00352 2/20 0.44
TDP1 Q9NUW8 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL511473 0.97 TSHR (0.60) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL15302954 0.97 TSHR (0.60) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL503550 0.97 TSHR (0.60) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL719958 0.97 TSHR (0.60) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL7609467 0.97 TSHR (0.60) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL8576746 0.97 TSHR (0.60) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL8573097 0.97 TSHR (0.60) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL16778332 0.97 TSHR (0.60) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL8574509 0.97 TSHR (0.60) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL8572239 0.97 TSHR (0.60) LMNATSHRNFKB1PMP22SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947123-B2 Synthetic caustic composition FLUID ENERGY GROUP LTD. (CA) 2021-03-16 US claimed
US-20190144741-A1 NOVEL SYNTHETIC CAUSTIC COMPOSITION HSBC BANK MIDDLE EAST LIMITED (AE) 2019-05-16 US claimed
CN-101547895-B Photoactive compounds AZ ELECTRONIC MATERIALS USA 2014-12-03 CN claimed
CN-101547895-A Photoactive compounds AZ ELECTRONIC MATERIALS USA (US) 2009-09-30 CN claimed
CN-101547913-A Photoactive compounds AZ ELECTRONIC MATERIALS USA (US) 2009-09-30 CN claimed
CN-101218225-A Photoactive compounds AZ ELECTRONIC MATERIALS USA (US) 2008-07-09 CN claimed
US-20240217983-A1 GPR119 AGONISTS KALLYOPE, INC. 2024-07-04 US disclosed
US-20240165139-A1 GALACTOPYRANOSYL-CYCLOHEXYL DERIVATIVES AS E-SELECTIN ANTAGONISTS GLYCOMIMETICS, INC. (US) 2024-05-23 US disclosed
EP-4320129-A1 GPR119 AGONISTS Kallyope, Inc. (US) 2024-02-14 EP disclosed
US-11878026-B2 Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists GLYCOMIMETICS, INC. (US) 2024-01-23 US disclosed
US-20220372398-A1 High Alkaline High Foam Cleaners with Controlled Foam Life HSBC BANK MIDDLE EAST LIMITED (AE) 2022-11-24 US disclosed
WO-2022236397-A1 HIGH ALKALINE HIGH FOAM CLEANERS WITH CONTROLLED FOAM LIFE FLUID ENERGY GROUP LTD. (CA) 2022-11-17 WO disclosed
WO-2022216709-A1 GPR119 AGONISTS KALLYOPE, INC. (US) 2022-10-13 WO disclosed
CN-101218225-A Photoactive compounds AZ ELECTRONIC MATERIALS USA (US) 2008-07-09 CN disclosed
CN-1509187-A Cytotoxic CD44 antibody immunoconjugates ���ָ��Ӣ��ķ�������Ϲ�˾ 2004-06-30 CN disclosed
EP-0062430-B1 PROCESS FOR THE PREPARATION OF (OMEGA-FLUOROSULFONYL) HALOALIPHATIC CARBOXYLIC ACID FLUORIDES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-11-12 EP disclosed
US-4466881-A ELECROLYTIC FLUORINATION ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-08-21 US disclosed
US-4425199-A FLUORINATION, ELECTROLYSIS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-01-10 US disclosed
EP-0062430-A1 Process for the preparation of (omega-fluorosulfonyl) haloaliphatic carboxylic acid fluorides Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-10-13 EP disclosed
US-4029744-A Process for removing the salt of a weak acid and a weak base from solution EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240217983-A1 GPR119 AGONISTS GPR119, GLP1R, GCGR LMNA 4659/4885TSHR 472/4885NFKB1 3559/4885
US-11878026-B2 Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists SELE, SELPLG, SELP LMNA 1122/4885TSHR 1766/4885NFKB1 1720/4885
US-20240165139-A1 GALACTOPYRANOSYL-CYCLOHEXYL DERIVATIVES AS E-SELECTIN ANTAGONISTS SELE, SELPLG, SELP LMNA 1122/4885TSHR 1766/4885NFKB1 1720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.