SCHEMBL5137019

SCHEMBL5137019

O=C1OCOC(=O)c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.58
TSHR P16473 2/20 0.58
ALOX15 P16050 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
MAOA P21397 4/20 0.54
MAOB P27338 2/20 0.54
ABCG2 Q9UNQ0 1/20 0.48
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
CDC25B P30305 2/20 0.45
KDM4E B2RXH2 3/20 0.43
POLB P06746 2/20 0.43
PTPRC P08575 2/20 0.43
CES1 P23141 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
CES2 O00748 1/20 0.43
APAF1 O14727 1/20 0.43
TERT O14746 1/20 0.43
NPC1 O15118 1/20 0.43
PLIN1 O60240 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1649257 0.85 PKM (0.75) PKMTSHRALOX15TDP1MAOA
Hydrochloric Acid SCHEMBL28645247 0.83 PKM (0.72) PKMTSHRALOX15TDP1MAOA
SCHEMBL3733365 0.82 ALOX15 (0.55) PKMTSHRALOX15TDP1MAOA
Hydrochloric Acid SCHEMBL23174308 0.80 ALOX15 (0.52) PKMTSHRALOX15TDP1MAOA
SCHEMBL1434255 0.80 ALOX15 (0.52) PKMTSHRALOX15TDP1MAOA
SCHEMBL30413722 0.78 MAOA (0.50) PKMTSHRALOX15TDP1MAOA
SCHEMBL13415918 0.78 MAOA (0.50) PKMTSHRALOX15TDP1MAOA
SCHEMBL29462577 0.78 MAOA (0.50) PKMTSHRALOX15TDP1MAOA
SCHEMBL24434352 0.78 MAOA (0.50) PKMTSHRALOX15TDP1MAOA
SCHEMBL5709796 0.78 MAOA (0.50) PKMTSHRALOX15TDP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240287228-A1 HOLLOW POLYMER PARTICLES AND METHOD FOR MANUFACTURING SAME SEKISUI KASEI CO., LTD. (JP) 2024-08-29 US disclosed
WO-2023026932-A1 COMPOSITION, CURED OBJECT, AND METHOD FOR PRODUCING CURED OBJECT 株式会社ADEKA 2023-03-02 WO disclosed
WO-2023282045-A1 COMPOUND, COMPOSITION, CURED PRODUCT, AND METHOD FOR PRODUCING CURED PRODUCT 株式会社ADEKA 2023-01-12 WO disclosed
EP-1957124-A2 METHODS OF BONDING OR MODIFYING HYDROGELS USING IRRADIATION ZIMMER INC. (US) 2008-08-20 EP disclosed
WO-2007067697-A2 METHODS OF BONDING OR MODIFYING HYDROGELS USING IRRADIATION ZIMMER, INC. (US) 2007-06-14 WO disclosed