SCHEMBL5137579

SCHEMBL5137579

CS(=O)(=O)C1(C(N)=O)CC1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.32
PKM P14618 1/20 0.32
KDM4E B2RXH2 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21822831 0.90 NPSR1 (0.39) NPSR1PKM
SCHEMBL12503609 0.88 NPSR1 (0.42) NPSR1
SCHEMBL27915505 0.78 NPSR1 (0.34) NPSR1
SCHEMBL7971343 0.76 CA1 (0.30)
SCHEMBL15428502 0.76 NPSR1 (0.33) NPSR1
SCHEMBL3309990 0.76 BLM (0.30) KDM4E
SCHEMBL18756627 0.73 DGAT1 (0.39) NPSR1
SCHEMBL26910776 0.73 SPHK1 (0.31)
Hydrochloric Acid SCHEMBL18725618 0.72 DGAT1 (0.38) NPSR1
SCHEMBL20447427 0.70 NPSR1 (0.59) NPSR1PKMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3774750-A1 IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF Betta Pharmaceuticals Co., Ltd (CN) 2021-02-17 EP claimed
US-20200360387-A1 CYCLOALKYL SUBSTITUTED PYRAZOLOPYRIMIDINES HAVING ACTIVITY AGAINST RSV JANSSEN-CILAG (FR) 2020-11-19 US claimed
WO-2019192506-A1 IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF BETTA PHARMACEUTICALS CO., LTD (CN) 2019-10-10 WO claimed
US-12617783-B2 Heterocyclic GLP-1R agonists BIOMEA FUSION, INC. (US) 2026-05-05 US disclosed
US-20250304572-A1 HETEROCYCLIC GLP-1R AGONISTS BIOMEA FUSION, INC. 2025-10-02 US disclosed
EP-3807254-A1 HETEROCYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF DISEASE Epigen Biosciences, Inc. (US) 2021-04-21 EP disclosed
EP-3774750-A1 IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF Betta Pharmaceuticals Co., Ltd (CN) 2021-02-17 EP disclosed
CN-110785408-A Modulators of indoleamine2, 3-dioxygenase 葛兰素史克知识产权开发有限公司 2020-02-11 CN disclosed
WO-2019192506-A1 IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF BETTA PHARMACEUTICALS CO., LTD (CN) 2019-10-10 WO disclosed
EP-2970155-A1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE (IDO) Bristol-Myers Squibb Company (US) 2016-01-20 EP disclosed
WO-2014150677-A1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE (IDO) BRISTOL-MYERS SQUIBB COMPANY (US) 2014-09-25 WO disclosed
WO-2008072077-A2 COMBINATION OF 1-ARYL-4-CYCLOPROPYLPYRAZOLES WITH ANTHELMINTIC AGENT FOR PARASITIC INFESTATION PFIZER LIMITED (GB) 2008-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304572-A1 HETEROCYCLIC GLP-1R AGONISTS GLP1R, GPR119, GIPR NPSR1 268/4885PKM 2709/4885KDM4E 3920/4885
US-20200360387-A1 CYCLOALKYL SUBSTITUTED PYRAZOLOPYRIMIDINES HAVING ACTIVITY AGAINST RSV ACE, ACE2, PTBP1 NPSR1 3124/4885PKM 575/4885KDM4E 2742/4885
US-12617783-B2 Heterocyclic GLP-1R agonists GLP1R, GIPR, GPR119 NPSR1 485/4885PKM 3810/4885KDM4E 2335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.