SCHEMBL5137828

SCHEMBL5137828

[Li]c1cc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10825969 0.88 LMNA (0.43) LMNA
SCHEMBL4933973 0.77 LMNA (0.40) LMNA
SCHEMBL4937888 0.77 LMNA (0.40) LMNA
SCHEMBL4938355 0.76 LMNA (0.33) LMNA
SCHEMBL4934552 0.76 LMNA (0.33) LMNA
SCHEMBL11046804 0.76 NR1H2 (0.36) LMNA
SCHEMBL10574915 0.76 NR1H2 (0.36) LMNA
SCHEMBL11046808 0.76 LMNA (0.33) LMNA
SCHEMBL4930840 0.76 LMNA (0.33) LMNA
SCHEMBL7932082 0.74 LMNA (0.31) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1888330-A2 CHEMICAL SENSOR The Regents of the University of Minnesota (US) 2008-02-20 EP disclosed
WO-2006127963-A2 CHEMICAL SENSOR REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2006-11-30 WO disclosed