SCHEMBL7932082

SCHEMBL7932082

[CH2]c1cc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10825969 0.85 LMNA (0.43) LMNA
SCHEMBL7923344 0.82
SCHEMBL18243020 0.79 TSHR (0.32)
SCHEMBL18243846 0.77
SCHEMBL6524841 0.76 LMNA (0.31) LMNA
SCHEMBL21166947 0.76 PGK1 (0.42) LMNA
SCHEMBL1119523 0.74 LMNA (0.35) LMNA
SCHEMBL5137828 0.74 LMNA (0.35) LMNA
SCHEMBL4933973 0.74 LMNA (0.40) LMNA
SCHEMBL4937888 0.74 LMNA (0.40) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0791607-B1 Substituted metallocene catalyst for the (co)polymerization of olefins ENICHEM SPA (IT) 2001-05-02 EP disclosed
US-5936051-A FORMING POLYMERS OF HIGH MOLECULAR WEIGHT; CHEMICAL AND HEAT RESISTANCE; ALUMOXANE COCATALYSTS ENICHEM S.P.A. (IT) 1999-08-10 US disclosed
EP-0791607-A2 Substituted metallocene catalyst for the (co)polymerization of olefins ENICHEM S.p.A. (IT) 1997-08-27 EP disclosed