SCHEMBL4938355

SCHEMBL4938355

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)c1cc([B-](c2cc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c2)(c2cc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c2)c2cc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c2)cc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4930840 1.00 LMNA (0.33) LMNA
SCHEMBL4934552 1.00 LMNA (0.33) LMNA
SCHEMBL4938720 0.98 LMNA (0.32) LMNA
SCHEMBL4938362 0.98 LMNA (0.32) LMNA
Potassium Ion SCHEMBL16669384 0.98 LMNA (0.32) LMNA
SCHEMBL10825969 0.86 LMNA (0.43) LMNA
SCHEMBL16669165 0.80
SCHEMBL4932994 0.78
SCHEMBL5137828 0.76 LMNA (0.35) LMNA
SCHEMBL4933973 0.76 LMNA (0.40) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8765060-B2 Chemical sensor REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2014-07-01 US claimed
US-20080293997-A1 Chemical Sensor NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-11-27 US claimed
EP-1888330-A2 CHEMICAL SENSOR The Regents of the University of Minnesota (US) 2008-02-20 EP claimed
WO-2006127963-A2 CHEMICAL SENSOR REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2006-11-30 WO claimed