SCHEMBL5138176

SCHEMBL5138176

CCc1ccc(CN)cc1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CSNK2A1 P68400 10/20 0.62
▸ CSNK2A2 P19784 1/20 0.62
▸ CSNK2B P67870 1/20 0.62
▸ CSNK2A3 Q8NEV1 1/20 0.62
▸ PNMT P11086 2/20 0.42
▸ KLK1 P06870 2/20 0.41
▸ KLKB1 P03952 1/20 0.41
▸ TAAR1 Q96RJ0 1/20 0.41
▸ LMNA P02545 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ NLRP1 Q9C000 1/20 0.40
▸ PSIP1 O75475 1/20 0.39
▸ LOX P28300 1/20 0.39
▸ LOXL3 P58215 1/20 0.39
▸ LOXL2 Q9Y4K0 1/20 0.39
▸ BACE1 P56817 1/20 0.39
▸ CYP3A4 P08684 1/20 0.38
▸ GRIN2D O15399 1/20 0.37
▸ GRIN3B O60391 1/20 0.37
▸ GRIN1 Q05586 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2006591 0.85 CSNK2A1 (0.52) CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT
SCHEMBL2602714 0.85 LMNA (0.46) CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT
SCHEMBL26325920 0.83 CSNK2A1 (0.49) CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT
SCHEMBL5847395 0.83 CSNK2A1 (0.57) CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT
SCHEMBL1696358 0.80 CSNK2A1 (0.49) CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT
SCHEMBL15047147 0.79 CSNK2A1 (0.47) CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT
SCHEMBL15778552 0.79 LMNA (0.43) CSNK2A1CSNK2A2CSNK2BCSNK2A3LMNA
SCHEMBL29277321 0.79 CSNK2A2 (0.41) CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT
SCHEMBL15107838 0.79 CNR1 (0.44) CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT
SCHEMBL17013472 0.79 CSNK2A1 (0.52) CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2008521903-A — — 2008-06-26 — — JP claimed
EP-1831206-A2 N-SUBSTITUTED BENZIMIDAZOLYL C-KIT INHIBITORS AND COMBINATORIAL BENZIMIDAZOLE LIBRARY OSI Pharmaceuticals, Inc. (US) 2007-09-12 — — EP claimed
WO-2006060381-A2 N-SUBSTITUTED BENZIMIDAZOLYL C-KIT INHIBITORS AND COMBINATORIAL BENZIMIDAZOLE LIBRARY OSI PHARMACEUTICALS, INC. (US) 2006-06-08 — — WO claimed
CN-104704052-B Anti-static flame retardant resin composition and its method and purposes 沙特基础全球技术有限公司 2017-03-08 — — CN disclosed
CN-101356235-B Polycarbonate compositions and articles formed therefrom, with matte surfaces and high light transmissions SABIC INNOVATIVE PLASTICS IP 2012-07-18 — — CN disclosed
CN-101360775-B High glass transition temperature copolycarbonates, methods of manufacture, and uses thereof GEN ELECTRIC 2012-06-27 — — CN disclosed
CN-101473246-B Infrared transmissive thermoplastic composition, and articles formed therefrom SABIC INNOVATIVE PLASTICS IP 2012-06-20 — — CN disclosed
CN-101553525-B Infrared transmissive thermoplastic composition SABIC INNOVATIVE PLASTICS IP 2012-05-23 — — CN disclosed
CN-102245690-A Flame retardant thermoplastic polycarbonate compositions SABIC INNOVATIVE PLASTICS IP 2011-11-16 — — CN disclosed
CN-101356212-B Copolycarbonate-polyesters, process for their preparation and their use SABIC INNOVATIVE PLASTICS IP 2011-11-09 — — CN disclosed
CN-101765635-A Flame retardant thermoplastic resin composition SABIC INNOVATIVE PLASTICS IP 2010-06-30 — — CN disclosed
CN-101553525-A Infrared transmissive thermoplastic composition SABIC INNOVATIVE PLASTICS IP (NL) 2009-10-07 — — CN disclosed
CN-101472994-A Polycarbonate compositions and articles formed therefrom GEN ELECTRIC (NL) 2009-07-01 — — CN disclosed
CN-101473246-A Infrared transmissive thermoplastic composition, and articles formed therefrom GEN ELECTRIC (NL) 2009-07-01 — — CN disclosed
CN-101395198-A Polyester oligomers, methods of making, and thermosetting compositions formed therefrom GEN ELECTRIC (US) 2009-03-25 — — CN disclosed
CN-101379114-A Thermally stable polycarbonates, thermoplastic compositions thereof, and articles made therefrom GEN ELECTRIC (US) 2009-03-04 — — CN disclosed
CN-101360775-A High glass transition temperature copolycarbonates, methods of manufacture, and uses thereof GEN ELECTRIC (US) 2009-02-04 — — CN disclosed
CN-101356212-A Copolycarbonate-polyesters, process for their preparation and their use GEN ELECTRIC (US) 2009-01-28 — — CN disclosed
CN-101356235-A Polycarbonate compositions and articles formed therefrom, with matte surfaces and high light transmissions GEN ELECTRIC (US) 2009-01-28 — — CN disclosed
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