SCHEMBL2602714

SCHEMBL2602714

CCc1ccc(CC)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
MAPK1 P28482 2/20 0.46
NLRP1 Q9C000 1/20 0.46
CSNK2A2 P19784 1/20 0.44
CSNK2B P67870 1/20 0.44
CSNK2A1 P68400 1/20 0.44
CSNK2A3 Q8NEV1 1/20 0.44
TRPA1 O75762 1/20 0.43
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
ALDH1A1 P00352 2/20 0.41
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772771 0.85 TRPA1 (0.43) LMNAMAPK1NLRP1CSNK2A2CSNK2B
SCHEMBL26325920 0.85 CSNK2A1 (0.49) LMNAMAPK1NLRP1CSNK2A2CSNK2B
SCHEMBL12763604 0.85 MAPK1 (0.40) LMNAMAPK1NLRP1CSNK2A2CSNK2B
SCHEMBL15778552 0.85 LMNA (0.43) LMNAMAPK1NLRP1CSNK2A2CSNK2B
SCHEMBL15107838 0.85 CNR1 (0.44) LMNAMAPK1NLRP1CSNK2A2CSNK2B
SCHEMBL29277321 0.85 CSNK2A2 (0.41) LMNAMAPK1NLRP1CSNK2A2CSNK2B
SCHEMBL5138176 0.85 CSNK2A1 (0.62) LMNAMAPK1NLRP1CSNK2A2CSNK2B
SCHEMBL6069968 0.82 CA2 (0.51) LMNAMAPK1NLRP1ALDH1A1KDM4C
SCHEMBL18075992 0.81 LMNA (0.41) LMNAMAPK1NLRP1CSNK2A2CSNK2B
SCHEMBL13761922 0.81 GABRA1 (0.47) LMNAMAPK1NLRP1CSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363892-A1 NASAL IMPLANTS AND SYSTEMS AND METHOD OF USE STRYKER CORPORATION 2023-11-16 US disclosed
US-11793911-B2 Stent made of a bio-degradable magnesium alloy with a magnesium fluoride coating and an organic coating MEKO LASERSTRAHL-MATERIALBEARBEITUNGEN E.K. (DE) 2023-10-24 US disclosed
US-11793911-B2 Stent made of a bio-degradable magnesium alloy with a magnesium fluoride coating and an organic coating MEKO LASERSTRAHL-MATERIALBEARBEITUNGEN E.K. (DE) 2023-10-24 US disclosed
US-11794290-B2 Method for forming cutters CNPC USA CORPORATION (US) 2023-10-24 US disclosed
US-11737865-B2 Nasal implants and systems and method of use SPIROX, INC. (US) 2023-08-29 US disclosed
EP-3541375-B1 FACTOR XIIA INHIBITORS MERCK SHARP & DOHME LLC (US) 2023-08-23 EP disclosed
US-20230181800-A1 COATED TUBING FOR MEDICAL ARTICLES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-06-15 US disclosed
US-11670804-B2 Scalable silicon anodes and the role of parylene films in improving electrode performance characteristics in energy storage systems RENSSELAER POLYTECHNIC INSTITUTE (US) 2023-06-06 US disclosed
US-20230149156-A1 Nasal Implants and Methods of Use STRYKER CORPORATION 2023-05-18 US disclosed
CN-108178724-B Process for the preparation of compounds 四川大学 2020-09-11 CN disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed
WO-2008019477-A1 VIRAL POLYMERASE INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-02-21 WO disclosed
US-7285565-B2 Benzamides and related inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-10-23 US disclosed
US-20070221958-A1 CIRCUIT BOARD AND MANUFACTURING METHOD THEREOF, ELECTRO-OPTICAL DEVICE, AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2007-09-27 US disclosed
US-20070215377-A1 CIRCUIT BOARD, ELECTRO-OPTICAL DEVICE, AND ELECTRIC APPARATUS SEIKO EPSON CORPORATION (JP) 2007-09-20 US disclosed
US-20070178710-A1 Method for sealing thin film transistors 3M INNOVATIVE PROPERTIES COMPANY 2007-08-02 US disclosed
US-20070096045-A1 Solid state radiation detector FUJIFILM CORPORATION 2007-05-03 US disclosed
US-20070042609-A1 Molecular caulk: a pore sealant for ultra-low k dielectrics RENSSELAER POLYTECHNIC INSTITUTE 2007-02-22 US disclosed
US-7179283-B2 Vapor deposition process for producing a stent-graft and a stent-graft produced therefrom SCIMED LIFE SYSTEMS, INC. (US) 2007-02-20 US disclosed
US-20070025883-A1 Uses of parylene membrane filters CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2007-02-01 US disclosed