Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 4/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2602714 | 0.85 | LMNA (0.46) | CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT | |
| SCHEMBL2006591 | 0.85 | CSNK2A1 (0.52) | CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT | |
| SCHEMBL5138176 | 0.83 | CSNK2A1 (0.62) | CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT | |
| SCHEMBL28098160 | 0.80 | TAAR1 (0.44) | CSNK2A1CSNK2A2CSNK2BCSNK2A3TAAR1 | |
| SCHEMBL12763604 | 0.79 | MAPK1 (0.40) | CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT | |
| SCHEMBL8772771 | 0.79 | TRPA1 (0.43) | CSNK2A1CSNK2A2CSNK2BCSNK2A3LMNA | |
| SCHEMBL15591097 | 0.78 | BACE1 (0.46) | CSNK2A1CSNK2A2CSNK2BCSNK2A3TAAR1 | |
| SCHEMBL10732579 | 0.78 | BACE1 (0.46) | CSNK2A1CSNK2A2CSNK2BCSNK2A3TAAR1 | |
| SCHEMBL23442587 | 0.77 | TAAR1 (0.41) | CSNK2A1CSNK2A2CSNK2BCSNK2A3TAAR1 | |
| SCHEMBL14183918 | 0.77 | TAAR1 (0.41) | CSNK2A1CSNK2A2CSNK2BCSNK2A3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234552-A2 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | Raze Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |