Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 8/20 | 0.65 |
| ▸ | FGFR2 | P21802 | 8/20 | 0.65 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.65 |
| ▸ | FGFR3 | P22607 | 8/20 | 0.65 |
| ▸ | SRC | P12931 | 5/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5138210 | 0.78 | PPARG (0.57) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL147279 | 0.78 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL5138100 | 0.77 | PPARG (0.56) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL13770821 | 0.71 | FGFR1 (0.85) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL5138445 | 0.69 | ALDH1A1 (0.38) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL5138007 | 0.69 | CDC25A (0.40) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL5138507 | 0.69 | ALDH1A1 (0.43) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL5138330 | 0.69 | CYP2A6 (0.43) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL5958299 | 0.69 | FGFR1 (0.70) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL28323064 | 0.69 | FGFR1 (0.52) | FGFR1FGFR2FGFR4FGFR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008037604-A1 | NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2008-04-03 | — | — | WO | claimed |
| WO-2008037604-A1 | NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2008-04-03 | — | — | WO | disclosed |