Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29108688 | 0.79 | FGFR1 (0.41) | ALDH1A1HSD17B10FGFR1FGFR2FGFR4 | |
| SCHEMBL5138330 | 0.74 | CYP2A6 (0.43) | ALDH1A1HSD17B10FGFR1FGFR2FGFR4 | |
| SCHEMBL5138507 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HSD17B10FGFR1FGFR2FGFR4 | |
| SCHEMBL5138007 | 0.74 | CDC25A (0.40) | ALDH1A1HSD17B10FGFR1FGFR2FGFR4 | |
| Hydrochloric Acid SCHEMBL7938606 | 0.71 | FGFR1 (0.35) | ALDH1A1HSD17B10FGFR1FGFR2FGFR4 | |
| SCHEMBL19879495 | 0.70 | ALDH1A1 (0.50) | ALDH1A1HSD17B10FGFR1FGFR2FGFR4 | |
| SCHEMBL5138388 | 0.69 | FGFR1 (0.65) | ALDH1A1FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL5138106 | 0.69 | MEN1 (0.39) | ALDH1A1FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL7023237 | 0.68 | ALDH1A1 (0.47) | ALDH1A1HSD17B10FGFR1FGFR2FGFR4 | |
| SCHEMBL14401541 | 0.66 | ALDH1A1 (0.44) | ALDH1A1HSD17B10FGFR1FGFR2FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008037604-A1 | NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2008-04-03 | — | — | WO | claimed |
| WO-2008037604-A1 | NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2008-04-03 | — | — | WO | disclosed |