Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532970 | 0.83 | ALDH1A1 (0.67) | ALDH1A1PDE4BMAPK1RAB9ANPC1 | |
| SCHEMBL532969 | 0.83 | ALDH1A1 (0.67) | ALDH1A1PDE4BMAPK1RAB9ANPC1 | |
| SCHEMBL852224 | 0.83 | ALDH1A1 (0.67) | ALDH1A1PDE4BMAPK1RAB9ANPC1 | |
| SCHEMBL8980173 | 0.79 | ALDH1A1 (0.61) | ALDH1A1PDE4BMAPK1RAB9ANPC1 | |
| SCHEMBL8440556 | 0.79 | ALDH1A1 (0.61) | ALDH1A1PDE4BMAPK1RAB9ANPC1 | |
| SCHEMBL31290735 | 0.79 | ALDH1A1 (0.61) | ALDH1A1PDE4BMAPK1RAB9ANPC1 | |
| SCHEMBL14401541 | 0.79 | ALDH1A1 (0.44) | ALDH1A1PDE4BMAPK1RAB9ANPC1 | |
| SCHEMBL7023222 | 0.75 | ALDH1A1 (0.40) | ALDH1A1PDE4BMAPK1RAB9ANPC1 | |
| Biphenyl SCHEMBL36559 | 0.71 | ALDH1A1 (0.90) | ALDH1A1MAPK1RAB9ANPC1CYP1A2 | |
| Biphenyl SCHEMBL1157981 | 0.71 | ALDH1A1 (0.90) | ALDH1A1MAPK1RAB9ANPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214762-B1 | REACTION OF METAL FULVENE COMPLEX AND UNSATURATED COMPOUND INSERTION COMPLEXES AND THE USE THEREOF AS CATALYSTS FOR THE POLYMERIZATION OF OLEFINS AND/OR DIENES AND AS HYDROGENATION CATALYSTS. | BAYER AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | claimed |
| CN-1245806-A | Catalyst based on metal fulvene compounding ingredient | BAYER AG (DE) | 2000-03-01 | — | — | CN | claimed |
| EP-0980872-A2 | Catalysts based upon fulvene-metal complexes | Bayer Aktiengesellschaft (DE) | 2000-02-23 | — | — | EP | claimed |
| US-9079768-B2 | Dehydrogenation of ammonia-borane by bifunctional catalysts | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-07-14 | — | — | US | disclosed |
| US-20120201744-A1 | Dehydrogenation of Ammonia-Borane by Bifunctional Catalysts | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2012-08-09 | — | — | US | disclosed |
| EP-1185541-B1 | CATALYST SYSTEM ON THE BASIS OF FULVENE COMPOUNDS | BAYER AG (DE) | 2003-01-15 | — | — | EP | disclosed |
| US-6403735-B1 | REACTING TRANSITION METAL COMPOUND WITH FULVENE COMPOUND IN PRESENCE OF REDUCING AGENT | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-11 | — | — | US | disclosed |
| EP-1185541-A1 | CATALYST SYSTEM ON THE BASIS OF FULVEN COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | disclosed |
| US-20020010084-A1 | Method for producting fulvene metal complexes | BECKE SIGURD (DE) | 2002-01-24 | — | — | US | disclosed |
| US-6258744-B1 | OLEFIN POLYMERIZATION CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-10 | — | — | US | disclosed |
| US-6214762-B1 | REACTION OF METAL FULVENE COMPLEX AND UNSATURATED COMPOUND INSERTION COMPLEXES AND THE USE THEREOF AS CATALYSTS FOR THE POLYMERIZATION OF OLEFINS AND/OR DIENES AND AS HYDROGENATION CATALYSTS. | BAYER AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| CN-1278265-A | Process for preparing fulvene metal complexes | BAYER AG (DE) | 2000-12-27 | — | — | CN | disclosed |
| WO-2000073315-A1 | CATALYST SYSTEM ON THE BASIS OF FULVEN COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-07 | — | — | WO | disclosed |
| EP-1028968-A1 | METHOD FOR PRODUCING FULVENE METAL COMPLEXES | BAYER AG (DE) | 2000-08-23 | — | — | EP | disclosed |
| CN-1246486-A | Catalyst system based on fulvene metal compound | BAYER AG (DE) | 2000-03-08 | — | — | CN | disclosed |
| EP-0982319-A2 | Catalyst system based on fulvene-cyclopentadienyl-metal complexes | Bayer Aktiengesellschaft (DE) | 2000-03-01 | — | — | EP | disclosed |
| CN-1245806-A | Catalyst based on metal fulvene compounding ingredient | BAYER AG (DE) | 2000-03-01 | — | — | CN | disclosed |
| EP-0980872-A2 | Catalysts based upon fulvene-metal complexes | Bayer Aktiengesellschaft (DE) | 2000-02-23 | — | — | EP | disclosed |
| WO-1999024445-A1 | METHOD FOR PRODUCING FULVENE METAL COMPLEXES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120201744-A1 | Dehydrogenation of Ammonia-Borane by Bifunctional Catalysts | IDH2, IDH1, IDH3A | ALDH1A1 1785/4885PDE4B 4770/4885MAPK1 4060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.