SCHEMBL5139133

SCHEMBL5139133

CCOc1cccc(C(=O)c2cccc(OCC)c2)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.68
KMT2A Q03164 3/20 0.68
ALDH1A1 P00352 3/20 0.68
MAPT P10636 2/20 0.68
KDM4E B2RXH2 1/20 0.68
MEN1 O00255 1/20 0.68
ALOX15 P16050 1/20 0.68
ALOX12 P18054 1/20 0.68
RECQL P46063 1/20 0.68
HSD17B10 Q99714 1/20 0.68
LMNA P02545 3/20 0.67
MAPK1 P28482 2/20 0.67
L3MBTL1 Q9Y468 2/20 0.67
SMN1; SMN2 Q16637 3/20 0.59
NR1H4 Q96RI1 1/20 0.57
HTT P42858 1/20 0.57
RXRA P19793 1/20 0.57
RXRB P28702 1/20 0.57
RAB9A P51151 3/20 0.56
NPC1 O15118 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18917584 0.95 L3MBTL1 (0.75) HPGDKMT2AALDH1A1MAPTKDM4E
SCHEMBL11003334 0.93 LMNA (0.78) HPGDKMT2AALDH1A1MAPTKDM4E
SCHEMBL4804575 0.89 TP53 (0.67) HPGDKMT2AALDH1A1MAPTKDM4E
SCHEMBL29505938 0.87 KMT2A (0.75) HPGDKMT2AALDH1A1MAPTKDM4E
SCHEMBL29505934 0.87 KMT2A (0.75) HPGDKMT2AALDH1A1MAPTKDM4E
SCHEMBL307233 0.87 KMT2A (0.75) HPGDKMT2AALDH1A1MAPTKDM4E
SCHEMBL1333545 0.87 KMT2A (0.75) HPGDKMT2AALDH1A1MAPTKDM4E
SCHEMBL11578212 0.85 MAPK1 (0.68) HPGDKMT2AALDH1A1MAPTKDM4E
SCHEMBL11044058 0.85 HPGD (0.56) HPGDKMT2AALDH1A1MAPTKDM4E
SCHEMBL364241 0.85 HPGD (0.56) HPGDKMT2AALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1771072-A2 SELECTIVE INSECTICIDES BASED ON HALOALKYLNICOTINIC ACID DERIVATIVES, ANTHRANILIC ACID DIAMIDES, OR PHTHALIC ACID DIAMIDES AND SAFENERS Bayer CropScience AG (DE) 2007-04-11 EP claimed
WO-2006008108-A2 SELECTIVE INSECTICIDES BASED ON HALOALKYLNICOTINIC ACID DERIVATIVES, ANTHRANILIC ACID DIAMIDES, OR PHTHALIC ACID DIAMIDES AND SAFENERS BAYER CROPSCIENCE AG (DE) 2006-01-26 WO claimed
US-10053526-B2 Catalyst for conjugated diene polymerization, conjugated diene polymer, modified conjugated diene polymer, polybutadiene, and compositions comprising foregoing UBE INDUSTRIES, LTD. (JP) 2018-08-21 US disclosed
US-20170158786-A1 CATALYST FOR CONJUGATED DIENE POLYMERIZATION, CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, POLYBUTADIENE, AND COMPOSITIONS COMPRISING FOREGOING UBE INDUSTRIES, LTD. (JP) 2017-06-08 US disclosed
CN-102884047-B 2-pyridone compounds NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-11-25 CN disclosed
EP-2411430-B1 PHOTORESIST COMPOSITION BASF SE (DE) 2015-10-14 EP disclosed
CN-102884047-A 2-pyridone compounds TAISHO PHARMACEUTICAL CO LTD 2013-01-16 CN disclosed
US-20080200499-A1 Selective Insecticides and/or Acaricides Based on Substituted Cyclic Dicarbonyl Compounds and Safeners BAYER CROPSCIENCE AG (DE) 2008-08-21 US disclosed
US-7148382-B2 Bathochromic mono- and bis-acylphosphine oxides and sulfides and their use as photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-12-12 US disclosed
US-20060257681-A1 Strongly adherent surface coatings CIBA SPECIALTY CHEMICALS CORP. 2006-11-16 US disclosed
US-20060160915-A1 Photocurable compositions CIBA SPECIALTY CHEMCIALS CORP. 2006-07-20 US disclosed
US-20040204613-A1 Bathochromic mono-and bis-acylphosphine oxides and sulfides and their use as photoinitiators IGM GROUP B.V. (NL) 2004-10-14 US disclosed
US-4042587-A PESTICIDES BASF AKTIENGESELLSCHAFT (DT) 1977-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200499-A1 Selective Insecticides and/or Acaricides Based on Substituted Cyclic Dicarbonyl Compounds and Safeners DDT, AADAC, ACMSD HPGD 2415/4885KMT2A 2611/4885ALDH1A1 2024/4885
US-20040204613-A1 Bathochromic mono-and bis-acylphosphine oxides and sulfides and their use as photoinitiators LBR, NR1H2, CBR1 HPGD 3059/4885KMT2A 3268/4885ALDH1A1 2374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.