SCHEMBL5139818

SCHEMBL5139818

[CH2]CC(=O)N(C)c1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
GAA P10253 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.38
NT5E P21589 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.36
TGM2 P21980 1/20 0.36
NSD2 O96028 1/20 0.36
TP53 P04637 1/20 0.35
HTT P42858 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11922926 0.83 KMT2A (0.41) KMT2AGAAMEN1LMNATDP1
SCHEMBL27544683 0.80 LMNA (0.43) KMT2AGAAMEN1LMNATDP1
SCHEMBL7825103 0.78 ALDH1A1 (0.46) KMT2AGAAMEN1LMNATSHR
SCHEMBL483015 0.78 HSD11B1 (0.48) KMT2AGAAMEN1LMNATSHR
Hydrochloric Acid SCHEMBL27809979 0.77 HSD11B1 (0.47) KMT2AGAAMEN1LMNATSHR
SCHEMBL7830528 0.77 DRD4 (0.46) KMT2AMEN1LMNATDP1TSHR
SCHEMBL98627 0.76 KMT2A (0.54) KMT2AMEN1ALDH1A1
SCHEMBL7826854 0.74 PPIB (0.49) LMNAALDH1A1SMN1; SMN2TP53HTT
SCHEMBL1134428 0.73 ALDH1A1 (0.55) KMT2AMEN1LMNATDP1TSHR
SCHEMBL27333040 0.71 ALDH1A1 (0.53) KMT2AMEN1LMNATDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7416835-B2 Polymerizable composition FUJIFILM CORPORATION (JP) 2008-08-26 US disclosed
US-20050106495-A1 Polymerizable composition FUJI PHOTO FILM CO., LTD. 2005-05-19 US disclosed