Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 13/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14539262 | 0.75 | RXRA (0.37) | ALDH1A1 | |
| SCHEMBL22613508 | 0.74 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL2082451 | 0.73 | HSD17B10 (0.47) | ALDH1A1 | |
| SCHEMBL2082178 | 0.73 | LMNA (0.42) | ALDH1A1 | |
| SCHEMBL26960987 | 0.72 | ALDH1A1 (0.41) | ALDH1A1PTGS2 | |
| SCHEMBL587682 | 0.71 | TAAR1 (0.42) | ALDH1A1 | |
| SCHEMBL3884112 | 0.71 | CYP19A1 (0.40) | ALDH1A1 | |
| SCHEMBL9047543 | 0.71 | TSHR (0.38) | ALDH1A1 | |
| SCHEMBL2084415 | 0.71 | LMNA (0.54) | ALDH1A1 | |
| SCHEMBL1932565 | 0.71 | TSHR (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611120-A4 | NOVEL METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASES | CORTICAL PTY LTD (AU) | 2008-04-23 | — | — | EP | disclosed |
| EP-1611120-A1 | NOVEL METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASES | Cortical Pty Ltd (AU) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004089927-A1 | NOVEL METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASES | CORTICAL PTY LTD (AU) | 2004-10-21 | — | — | WO | disclosed |