Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5140534 | 0.78 | MITF (0.49) | L3MBTL1MITFALDH1A1PTGS1PTGS2 | |
| SCHEMBL5353581 | 0.73 | MITF (0.46) | MITFALDH1A1LMNAKDM4E | |
| SCHEMBL21291552 | 0.72 | GAA (0.37) | L3MBTL1MITFALDH1A1CYP2C19LMNA | |
| SCHEMBL21362773 | 0.71 | PTGS1 (0.39) | L3MBTL1TDP1PTGS1PTGS2RXFP1 | |
| SCHEMBL7489316 | 0.71 | RXFP1 (0.42) | L3MBTL1TDP1ALDH1A1PTGS1PTGS2 | |
| SCHEMBL1051401 | 0.69 | PTGER1 (0.39) | L3MBTL1TDP1ALDH1A1PTGS1PTGS2 | |
| SCHEMBL375420 | 0.69 | RXFP1 (0.45) | L3MBTL1TDP1ALDH1A1PTGS1PTGS2 | |
| SCHEMBL18776163 | 0.69 | PTGS1 (0.38) | L3MBTL1TDP1PTGS1PTGS2RXFP1 | |
| Hydrochloric Acid SCHEMBL31555571 | 0.69 | RXFP1 (0.41) | L3MBTL1TDP1ALDH1A1PTGS1PTGS2 | |
| SCHEMBL1559275 | 0.69 | L3MBTL1 (0.63) | L3MBTL1MITFALDH1A1CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896040-A2 | PHOSPHORAMIDATE ALKYLATOR PRODRUGS | Threshold Pharmaceuticals, Inc. (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007002931-A2 | PHOSPHORAMIDATE ALKYLATOR PRODRUGS | THRESHOLD PHARMACEUTICALS, INC. (US) | 2007-01-04 | — | — | WO | disclosed |