Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29716077 | 0.83 | KDM4E (0.38) | KDM4ETSHRBRD4L3MBTL1 | |
| SCHEMBL29304587 | 0.81 | RXFP1 (0.36) | PTGS1PTGS2RXFP1KDM4EALOX15 | |
| SCHEMBL10423801 | 0.78 | ALDH1A1 (0.34) | PTGS1RXFP1KDM4ETSHRL3MBTL1 | |
| SCHEMBL7489316 | 0.78 | RXFP1 (0.42) | PTGS1PTGS2RXFP1KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL31555571 | 0.77 | RXFP1 (0.41) | PTGS1PTGS2RXFP1KDM4EALOX15 | |
| SCHEMBL20833591 | 0.77 | L3MBTL1 (0.31) | TDP1L3MBTL1 | |
| SCHEMBL781347 | 0.77 | GABRP (0.37) | KDM4ETSHRL3MBTL1 | |
| SCHEMBL1051401 | 0.77 | PTGER1 (0.39) | PTGS1PTGS2RXFP1KDM4EALOX15 | |
| SCHEMBL375420 | 0.77 | RXFP1 (0.45) | PTGS1PTGS2RXFP1KDM4EALOX15 | |
| SCHEMBL18776163 | 0.77 | PTGS1 (0.38) | PTGS1PTGS2RXFP1KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019174277-A1 | PHOSPHOETHANOLAMINE TRANSFERASE INHIBITORS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2019-09-19 | — | — | WO | disclosed |