Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.37 |
| ▸ | DPP4 | P27487 | 6/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7557605 | 0.82 | — | — | |
| SCHEMBL1615523 | 0.78 | OPRM1 (0.39) | DPP7DPP4DPP8DPP9OPRM1 | |
| SCHEMBL1615233 | 0.76 | OPRM1 (0.48) | OPRM1 | |
| SCHEMBL28298745 | 0.74 | OPRM1 (0.46) | OPRM1 | |
| SCHEMBL28298671 | 0.74 | OPRM1 (0.46) | OPRM1 | |
| SCHEMBL1615271 | 0.74 | OPRM1 (0.46) | OPRM1 | |
| SCHEMBL28300172 | 0.74 | OPRM1 (0.46) | OPRM1 | |
| SCHEMBL1614359 | 0.74 | OPRM1 (0.46) | OPRM1 | |
| SCHEMBL2914564 | 0.74 | HRH3 (0.40) | DPP7DPP4DPP8DPP9OPRM1 | |
| SCHEMBL1614413 | 0.74 | OPRM1 (0.46) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2055302-B1 | Method for the improvement of islet signaling in diabetes mellitus and for its prevention | ROYALTY PHARMA COLLECTION TRUST (US) | 2014-09-10 | — | — | EP | claimed |
| EP-1283735-B2 | METHOD FOR THE IMPROVEMENT OF ISLET SIGNALING IN DIABETES MELLITUS AND FOR ITS PREVENTION | ROYALTY PHARMA COLLECTION TRUST (US) | 2012-10-24 | — | — | EP | claimed |
| EP-1283735-B1 | METHOD FOR THE IMPROVEMENT OF ISLET SIGNALING IN DIABETES MELLITUS AND FOR ITS PREVENTION | PROSIDION LTD (GB) | 2008-12-31 | — | — | EP | claimed |