Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 10/20 | 0.55 |
| ▸ | CSGALNACT1 | Q8TDX6 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088907 | 0.83 | DGAT1 (0.58) | DGAT1CSGALNACT1NPSR1HDAC1HDAC6 | |
| SCHEMBL3121185 | 0.83 | DGAT1 (0.58) | DGAT1CSGALNACT1NPSR1HDAC1HDAC6 | |
| SCHEMBL3096212 | 0.74 | DGAT1 (0.80) | DGAT1CSGALNACT1 | |
| SCHEMBL3095825 | 0.74 | DGAT1 (0.80) | DGAT1CSGALNACT1 | |
| SCHEMBL21274594 | 0.73 | CA2 (0.63) | DGAT1CSGALNACT1NPSR1CA2CA1 | |
| SCHEMBL21274591 | 0.73 | CA2 (0.63) | DGAT1CSGALNACT1NPSR1CA2CA1 | |
| SCHEMBL3099772 | 0.72 | DGAT1 (0.80) | DGAT1CSGALNACT1 | |
| SCHEMBL3100460 | 0.72 | DGAT1 (0.80) | DGAT1CSGALNACT1 | |
| SCHEMBL3094969 | 0.71 | DGAT1 (0.71) | DGAT1CSGALNACT1CA2CA1 | |
| SCHEMBL4760256 | 0.70 | DGAT1 (0.62) | DGAT1NPSR1CA2CA1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912634-A2 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | Bayer Healthcare, LLC (US) | 2008-04-23 | — | — | EP | claimed |
| WO-2007016538-A2 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2007-02-08 | — | — | WO | claimed |