SCHEMBL5141035

SCHEMBL5141035

C=CC(N)c1cccc2[nH]c(=O)c(Cc3ccccc3)nc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.54
▸ KDM4E B2RXH2 3/20 0.54
▸ HTT P42858 2/20 0.54
▸ GAA P10253 2/20 0.54
▸ HPGD P15428 2/20 0.54
▸ HSD17B10 Q99714 1/20 0.54
▸ NPC1 O15118 2/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ PKM P14618 1/20 0.41
▸ CYP2C9 P11712 1/20 0.40
▸ HTR2C P28335 1/20 0.40
▸ LTB4R Q15722 1/20 0.37
▸ POLB P06746 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ PNP P00491 3/20 0.36
▸ HTR6 P50406 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30019636 0.75 GAA (0.64) ALDH1A1KDM4EHTTGAAHPGD
SCHEMBL23886103 0.75 GAA (0.64) ALDH1A1KDM4EHTTGAAHPGD
SCHEMBL6490997 0.71 KDM4E (1.00) ALDH1A1KDM4EHTTGAAHPGD
SCHEMBL7071593 0.63 HPGD (0.53) ALDH1A1HPGDSMN1; SMN2PARP1
SCHEMBL1783621 0.63 — —
SCHEMBL666673 0.63 DPP4 (0.33) ALDH1A1
SCHEMBL5666708 0.62 ALDH1A1 (0.39) ALDH1A1KDM4EHTTGAAHPGD
SCHEMBL7480542 0.62 IMPDH2 (0.46) ALDH1A1KDM4EHTTGAAHPGD
SCHEMBL28479646 0.62 KDM4E (0.72) ALDH1A1KDM4EHTTGAAHPGD
SCHEMBL9636427 0.62 GAA (0.54) ALDH1A1KDM4EGAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1009316-A4 APPARATUS AND METHOD FOR AN AUDITORY STIMULATOR BAUMAN NATAN (US) 2008-11-19 — — EP disclosed
EP-1009316-A1 APPARATUS AND METHOD FOR AN AUDITORY STIMULATOR Bauman, Natan (US) 2000-06-21 — — EP disclosed
WO-1999007302-A1 APPARATUS AND METHOD FOR AN AUDITORY STIMULATOR BAUMAN NATAN (US) 1999-02-18 — — WO disclosed
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