Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 3/20 | 0.43 |
| ▸ | SI | P14410 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23886103 | 1.00 | GAA (0.64) | GAAALDH1A1HTTHPGDKDM4E | |
| SCHEMBL6542830 | 0.81 | GAA (0.60) | GAAALDH1A1ALKBH3NPC1RAB9A | |
| SCHEMBL6490997 | 0.78 | KDM4E (1.00) | GAAALDH1A1HTTHPGDKDM4E | |
| SCHEMBL30019420 | 0.78 | GAA (0.62) | GAAALDH1A1HTTHPGDKDM4E | |
| SCHEMBL23886073 | 0.78 | GAA (0.62) | GAAALDH1A1HTTHPGDKDM4E | |
| SCHEMBL10285823 | 0.76 | MGAM (0.50) | GAAALDH1A1TDP1AURKAESR1 | |
| SCHEMBL14844694 | 0.76 | KDM4E (0.59) | GAAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL5141035 | 0.75 | ALDH1A1 (0.54) | GAAALDH1A1HTTHPGDKDM4E | |
| SCHEMBL6753947 | 0.73 | RAB9A (0.59) | GAAALDH1A1ALKBH3NPC1RAB9A | |
| SCHEMBL6697342 | 0.71 | DRD2 (0.50) | GAAALDH1A1ALKBH3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115485273-B | N- (heterocyclyl and heterocyclylalkyl) -3-benzyl pyridin-2-amine derivatives as SSTR4 agonists | 武田药品工业株式会社 | 2024-08-13 | — | — | CN | disclosed |
| EP-4126849-A1 | N-(HETEROCYCLYL AND HETEROCYCLYLALKYL)-3-BENZYLPYRIDIN-2-AMINE DERIVATIVES AS SSTR4 AGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2023-02-08 | — | — | EP | disclosed |
| CN-115485273-A | N- (heterocyclyl and heterocyclylalkyl) -3-benzylpyridin-2-amine derivatives as SSTR4 agonists | 武田药品工业株式会社 | 2022-12-16 | — | — | CN | disclosed |