SCHEMBL5141144

SCHEMBL5141144

C=C(C)OC(=O)C(C)=COCCO

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27388489 0.87 ALDH1A1 (0.34) TSHR
SCHEMBL28395297 0.85 ALDH1A1 (0.35) HSD17B10TDP1TSHR
SCHEMBL25200990 0.82 TSHR (0.46) HSD17B10TSHR
SCHEMBL29020460 0.79 MGAM (0.38)
SCHEMBL28968670 0.79 THRB (0.49) TDP1TSHR
SCHEMBL8629629 0.79 TSHR (0.39) TSHR
SCHEMBL898881 0.79 ALDH1A1 (0.34) TDP1TSHR
SCHEMBL27392259 0.78 THRB (0.38) TSHR
SCHEMBL27999171 0.78 THRB (0.38) TSHR
SCHEMBL27295436 0.78 THRB (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200324018-A1 ENDOLUMINAL DEVICE AND POLYMER SILICON VALLEY BANK 2020-10-15 US disclosed
EP-3700465-A1 ENDOLUMINAL DEVICE AND POLYMER Endologix, Inc. (US) 2020-09-02 EP disclosed
US-20080171836-A1 BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR KENSEY NASH CORPORATION 2008-07-17 US disclosed