Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629629 | 0.87 | TSHR (0.39) | THRBTSHR | |
| SCHEMBL27388489 | 0.84 | ALDH1A1 (0.34) | THRBTSHRALDH1A1 | |
| SCHEMBL28701636 | 0.83 | TSHR (0.56) | THRBTSHRALDH1A1 | |
| SCHEMBL27621039 | 0.83 | THRB (0.49) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL28087290 | 0.82 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL26980911 | 0.82 | ACHE (0.37) | THRBTSHRALDH1A1POLB | |
| SCHEMBL7623060 | 0.81 | THRB (0.63) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL937816 | 0.80 | GLO1 (0.42) | THRBTSHRALDH1A1 | |
| SCHEMBL21836015 | 0.80 | THRB (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL28707259 | 0.80 | THRB (0.39) | THRBTSHRALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115814158-B | Wear-resistant lubricating coating similar to articular cartilage and preparation method thereof | 中山大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-115779159-B | High-strength and high-toughness wear-resistant hydrophilic lubricating coating grafted on surface of medical instrument and preparation method thereof | 中山大学 | 2024-01-16 | — | — | CN | disclosed |
| CN-115779159-B | High-strength and high-toughness wear-resistant hydrophilic lubricating coating grafted on surface of medical instrument and preparation method thereof | 中山大学 | 2024-01-16 | — | — | CN | disclosed |
| CN-115814158-A | Articular cartilage-like wear-resistant lubricating coating and preparation method thereof | 中山大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-115779159-A | High-strength-toughness wear-resistant hydrophilic lubricating coating grafted on surface of medical instrument and preparation method thereof | 中山大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-115779159-A | High-strength-toughness wear-resistant hydrophilic lubricating coating grafted on surface of medical instrument and preparation method thereof | 中山大学 | 2023-03-14 | — | — | CN | disclosed |