Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5974838 | 0.98 | ALDH1A1 (0.53) | ALDH1A1KDM4ETDP1TSHRPOLB | |
| SCHEMBL5069507 | 0.96 | TSHR (0.58) | ALDH1A1KDM4ETDP1TSHRPOLB | |
| Hydrochloric Acid SCHEMBL3851608 | 0.95 | TSHR (0.57) | ALDH1A1KDM4ETDP1TSHRPOLB | |
| Bromide SCHEMBL7057614 | 0.81 | HTR1A (0.43) | ALDH1A1KDM4ETDP1TSHRPOLB | |
| SCHEMBL5071137 | 0.81 | LMNA (0.51) | ALDH1A1TSHRPOLBSMN1; SMN2RAB9A | |
| SCHEMBL5069524 | 0.81 | LMNA (0.51) | ALDH1A1TSHRPOLBSMN1; SMN2RAB9A | |
| SCHEMBL5070436 | 0.81 | LMNA (0.51) | ALDH1A1TSHRPOLBSMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL5071101 | 0.80 | LMNA (0.50) | ALDH1A1TSHRPOLBSMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL5069533 | 0.80 | LMNA (0.50) | ALDH1A1TSHRPOLBSMN1; SMN2RAB9A | |
| Bromide SCHEMBL3846115 | 0.80 | LMNA (0.54) | ALDH1A1TSHRPOLBSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1128830-B1 | REVERSING ADVANCED GLYCOSYLATION CROSS-LINKS USING HETEROCYCLIC-SUBSTITUTED THIAZOLIUM SALTS | SYNVISTA THERAPEUTICS INC (US) | 2008-03-12 | — | — | EP | claimed |