Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27189775 | 0.81 | LMNA (0.38) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL7839805 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL26607151 | 0.75 | MEN1 (0.39) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL8938822 | 0.71 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL5666036 | 0.71 | CA1 (0.44) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL10909721 | 0.70 | METAP1 (0.42) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL16167829 | 0.69 | CYP3A4 (0.45) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL26607327 | 0.69 | MALT1 (0.40) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL26607342 | 0.69 | MAPT (0.43) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL3949987 | 0.68 | TUBB4A (0.47) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004664-A1 | METALLOCENE COMPOUNDS | Basell Polyolefine GmbH (DE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007116034-A1 | METALLOCENE COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |