Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2091697 | 0.83 | PIM1 (0.33) | EPHX2PIM1PIM2MAOBAOC3 | |
| SCHEMBL2093876 | 0.82 | GPR3 (0.35) | EPHX2PIM1PIM2MAOBAOC3 | |
| SCHEMBL6454577 | 0.80 | ALDH1A1 (0.38) | CA12CA9KDM4E | |
| SCHEMBL254957 | 0.80 | MAPT (0.56) | EPHX2PIM1PIM2MAOBAOC3 | |
| SCHEMBL2091935 | 0.79 | CHRM2 (0.47) | PIM1PIM2MAPTGAAKIF11 | |
| SCHEMBL30214321 | 0.79 | CHRM2 (0.47) | PIM1PIM2MAPTGAAKIF11 | |
| SCHEMBL535404 | 0.77 | MAPT (0.42) | EPHX2PIM1PIM2MAOBAOC3 | |
| SCHEMBL7658787 | 0.77 | MAPT (0.42) | EPHX2PIM1PIM2MAOBAOC3 | |
| SCHEMBL2090989 | 0.77 | TDP1 (0.40) | MAPTKMT2AKIF11KDM4ECYP2D6 | |
| SCHEMBL513897 | 0.77 | CA1 (0.48) | PIM1PIM2MAOBAOC3KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354297-B1 | THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDAL AND ACARICIDAL AGENTS COMPRISING THE THIADIAZINES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-08-05 | — | — | EP | claimed |
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| EP-2719688-B1 | Process for producing tetrazolyloxime derivatives | NIPPON SODA CO (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-2719686-B1 | Process to halogenate a picoline derivative | NIPPON SODA CO (JP) | 2015-12-02 | — | — | EP | disclosed |
| EP-2719687-B1 | Process to make a bromopicoline derivative | NIPPON SODA CO (JP) | 2015-09-16 | — | — | EP | disclosed |
| US-9018385-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-04-28 | — | — | US | disclosed |
| US-9012653-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9000178-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-04-07 | — | — | US | disclosed |
| US-8962848-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-02-24 | — | — | US | disclosed |
| WO-2014184070-A1 | MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES | SYNGENTA LIMITED (GB) | 2014-11-20 | — | — | WO | disclosed |
| EP-1862453-A1 | MONOMOLECULAR CONDUCTIVE COMPLEX, CONDUCTIVE SELF-ASSEMBLED FILM AND ASSEMBLY OF ELECTRODE COMPOSED OF METAL AND SEMICONDUCTOR MAKING USE OF THE SAME | Tokyo Institute of Technology (JP) | 2007-12-05 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| CN-1729178-A | N-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and piperazines | FMC CORP (US) | 2006-02-01 | — | — | CN | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| EP-0354297-B1 | THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDAL AND ACARICIDAL AGENTS COMPRISING THE THIADIAZINES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-08-05 | — | — | EP | disclosed |
| US-5021412-A | Protecting agricultural crops | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0354297-A1 | Thiadiazines, process for production thereof, and insecticidal and acaricidal agents comprising the thiadiazines | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | EPHX2 3662/4885PIM1 3129/4885PIM2 2557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.