Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 13/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557057 | 0.80 | GNAI3 (0.47) | — | |
| SCHEMBL11794036 | 0.80 | GNAI3 (0.47) | — | |
| Bromide SCHEMBL28185708 | 0.79 | GNAI3 (0.46) | — | |
| Bromide SCHEMBL28185105 | 0.79 | GNAI3 (0.46) | — | |
| Bromide SCHEMBL29089345 | 0.79 | GNAI3 (0.46) | — | |
| Hydrazine SCHEMBL8557307 | 0.77 | GNAI3 (0.45) | — | |
| SCHEMBL27690567 | 0.72 | SLC6A2 (0.47) | SLC6A2ADRB2SLC6A4SLC6A3 | |
| SCHEMBL6028682 | 0.71 | KCNH2 (0.34) | SLC6A2ADRB2HTR1AHTR2ASLC6A4 | |
| SCHEMBL372823 | 0.71 | — | — | |
| SCHEMBL18284760 | 0.68 | SLC6A2 (0.63) | SLC6A2SSTR4ADRB2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091745-B1 | TREATMENT OF HYPERPROLIFERATIVE DISORDERS | CHILDREN S HOSPITAL LOS ANGELE (US) | 2008-10-01 | — | — | EP | claimed |