Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 5/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.47 |
| ▸ | GBA1 | P04062 | 6/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | FUCA1 | P04066 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11794036 | 1.00 | GNAI3 (0.47) | GNAI3GNAO1GNAI1GBA1EPHX1 | |
| Bromide SCHEMBL29089345 | 0.98 | GNAI3 (0.46) | GNAI3GNAO1GNAI1GBA1EPHX1 | |
| Bromide SCHEMBL28185105 | 0.98 | GNAI3 (0.46) | GNAI3GNAO1GNAI1GBA1EPHX1 | |
| Bromide SCHEMBL28185708 | 0.98 | GNAI3 (0.46) | GNAI3GNAO1GNAI1GBA1EPHX1 | |
| Hydrazine SCHEMBL8557307 | 0.97 | GNAI3 (0.45) | GNAI3GNAO1GNAI1GBA1EPHX1 | |
| SCHEMBL6028682 | 0.86 | KCNH2 (0.34) | GNAI3GNAO1GNAI1 | |
| SCHEMBL372823 | 0.86 | — | — | |
| SCHEMBL5141998 | 0.80 | SLC6A2 (0.43) | — | |
| SCHEMBL1654781 | 0.78 | — | — | |
| SCHEMBL29060491 | 0.75 | SLC6A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |
| US-5424451-A | Used as cholinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |
| US-5302593-A | Aminoalkylcarbamic esters of eseroline suitable for use as chlorinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1994-04-12 | — | — | US | disclosed |
| EP-0575954-A1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-12-29 | — | — | EP | disclosed |